Department of Cell and Developmental Biology

2008

A chromatin immunoprecipitation screen in mouse keratinocytes reveals Runx1 as a direct transcriptional target of ΔNp63

Ortt, K., Raveh, E., Gat, U. & Sinha, S., 1 Jul 2008, In: Journal of Cellular Biochemistry. 104, 4, p. 1204-1219 16 p.

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Activation and transposition of endogenous retroviral elements in hypomethylation induced tumors in mice

Howard, G., Eiges, R., Gaudet, F., Jaenisch, R. & Eden, A., 10 Jan 2008, In: Oncogene. 27, 3, p. 404-408 5 p.

Research output: Contribution to journal › Article › peer-review

287 Scopus citations

The evolutionary origin of the Runx/CBFbeta transcription factors - Studies of the most basal metazoans

Sullivan, J. C., Sher, D., Eisenstein, M., Shigesada, K., Reitzel, A. M., Marlow, H., Levanon, D., Groner, Y., Finnerty, J. R. & Gat, U., 2008, In: BMC Evolutionary Biology. 8, 1, 228.

Research output: Contribution to journal › Article › peer-review

Open Access

42 Scopus citations

Transcriptional activation of a subset of hair keratin genes by the NF-κB effector p65/RelA

Gilon, M., Sher, N., Cohen, S. & Gat, U., Jun 2008, In: Differentiation. 76, 5, p. 518-530 13 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

2007

A model for the structure of the C-terminal domain of dragline spider silk and the role of its conserved cysteine

Ittah, S., Michaeli, A., Goldblum, A. & Gat, U., Sep 2007, In: Biomacromolecules. 8, 9, p. 2768-2773 6 p.

Research output: Contribution to journal › Article › peer-review

41 Scopus citations

A Rab-GAP TBC domain protein binds hepatitis C virus NS5A and mediates viral replication

Sklan, E. H., Staschke, K., Oakes, T. M., Elazar, M., Winters, M., Aroeti, B., Danieli, T. & Glenn, J. S., Oct 2007, In: Journal of Virology. 81, 20, p. 11096-11105 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

68 Scopus citations

Cholesterol-sensitive modulation of transcytosis

Leyt, J., Melamed-Book, N., Vaerman, J. P., Cohen, S., Weiss, A. M. & Aroeti, B., Jun 2007, In: Molecular Biology of the Cell. 18, 6, p. 2057-2071 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Developmental Study of Fragile X Syndrome Using Human Embryonic Stem Cells Derived from Preimplantation Genetically Diagnosed Embryos

Eiges, R., Urbach, A., Malcov, M., Frumkin, T., Schwartz, T., Amit, A., Yaron, Y., Eden, A., Yanuka, O., Benvenisty, N. & Ben-Yosef, D., 15 Nov 2007, In: Cell Stem Cell. 1, 5, p. 568-577 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

244 Scopus citations

Inactivation of Myocardin and p16 during Malignant Transformation Contributes to a Differentiation Defect

Milyavsky, M., Shats, I., Cholostoy, A., Brosh, R., Buganim, Y., Weisz, L., Kogan, I., Cohen, M., Shatz, M., Madar, S., Kalo, E., Goldfinger, N., Yuan, J., Ron, S., MacKenzie, K., Eden, A. & Rotter, V., 13 Feb 2007, In: Cancer Cell. 11, 2, p. 133-146 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

66 Scopus citations

2006

An essential role for the C-terminal domain of a dragline spider silk protein in directing fiber formation

Ittah, S., Cohen, S., Garty, S., Cohn, D. & Gat, U., Jun 2006, In: Biomacromolecules. 7, 6, p. 1790-1795 6 p.

Research output: Contribution to journal › Article › peer-review

81 Scopus citations

A novel role for the choroid plexus in BMP-mediated inhibition of differentiation of cerebellar neural progenitors

Krizhanovsky, V. & Ben-Arie, N., Jan 2006, In: Mechanisms of Development. 123, 1, p. 67-75 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

43 Scopus citations

Dynamic expression of Runx1 in skin affects hair structure

Raveh, E., Cohen, S., Levanon, D., Negreanu, V., Groner, Y. & Gat, U., Nov 2006, In: Mechanisms of Development. 123, 11, p. 842-850 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

36 Scopus citations

Infrared surface plasmon resonance: A novel tool for real time sensing of variations in living cells

Ziblat, R., Lirtsman, V., Davidov, D. & Aroeti, B., Apr 2006, In: Biophysical Journal. 90, 7, p. 2592-2599 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

110 Scopus citations

Math1 target genes are enriched with evolutionary conserved clustered E-box binding sites

Krizhanovsky, V., Soreq, L., Kliminski, V. & Ben-Arie, N., 2006, In: Journal of Molecular Neuroscience. 28, 2, p. 211-229 19 p.

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

2005

BjαIT: A novel scorpion α-toxin selective for insects - Unique pharmacological tool

Arnon, T., Potikha, T., Sher, D., Elazar, M., Mao, W., Tal, T., Bosmans, F., Tytgat, J., Ben-Arie, N. & Zlotkin, E., Mar 2005, In: Insect Biochemistry and Molecular Biology. 35, 3, p. 187-195 9 p.

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Clearing and photography of whole mount X-gal stained mouse embryos

Schatz, O., Golenser, E. & Ben-Arie, N., 2005, In: BioTechniques. 39, 5, p. 650-653 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis

Yamada, Y., Jackson-Grusby, L., Linhart, H., Meissner, A., Eden, A., Lin, H. & Jaenisch, R., 20 Sep 2005, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 38, p. 13580-13585 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

222 Scopus citations

Recombinant cells produce spider silk fibers

Scheibel, T. & Gat, U., Jan 2005, Industrial Bioprocessing, 27, 1, p. 10 1 p.

Research output: Contribution to specialist publication › Article

Runx3 is involved in hair shape determination

Raveh, E., Cohen, S., Levanon, D., Groner, Y. & Gat, U., Aug 2005, In: Developmental Dynamics. 233, 4, p. 1478-1487 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

36 Scopus citations

2004

Dual Control of Neurogenesis by PC3 through Cell Cycle Inhibition and Induction of Math1

Canzoniere, D., Farioli-Vecchioli, S., Conti, F., Ciotti, M. T., Tata, A. M., Augusti-Tocco, G., Mattei, E., Lakshmana, M. K., Krizhanovsky, V., Reeves, S. A., Giovannoni, R., Castano, F., Servadio, A., Ben-Arie, N. & Tirone, F., 31 Mar 2004, In: Journal of Neuroscience. 24, 13, p. 3355-3369 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

75 Scopus citations

Genotype identification of Math1/LacZ knockout mice based on real-time PCR with SYBR Green I dye

Krizhanovsky, V., Golenser, E. & Ben-Arie, N., 30 Jul 2004, In: Journal of Neuroscience Methods. 136, 2, p. 187-192 6 p.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Hepatitis C virus core protein associates with detergent-resistant membranes distinct from classical plasma membrane rafts

Matto, M., Rice, C. M., Aroeti, B. & Glenn, J. S., Nov 2004, In: Journal of Virology. 78, 21, p. 12047-12053 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

42 Scopus citations

Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway

Gazit, R., Krizhanovsky, V. & Ben-Arie, N., Feb 2004, In: Journal of Embryology and Experimental Morphology. 131, 4, p. 903-913 11 p.

Research output: Contribution to journal › Article › peer-review

91 Scopus citations

Novel assembly properties of recombinant spider dragline silk proteins

Huemmerich, D., Scheibel, T., Vollrath, F., Cohen, S., Gat, U. & Ittah, S., 23 Nov 2004, In: Current Biology. 14, 22, p. 2070-2074 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

166 Scopus citations

2003

Polar expression of ErbB-2/HER2 in epithelia: Bimodal regulation by Lin-7

Shelly, M., Mosesson, Y., Citri, A., Lavi, S., Zwang, Y., Melamed-Book, N., Aroeti, B. & Yarden, Y., 1 Sep 2003, In: Developmental Cell. 5, 3, p. 475-486 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

60 Scopus citations

2002

Alternative splicing and neuritic mRNA translocation under long-term neuronal hypersensitivity

Meshorer, E., Erb, C., Gazit, R., Pavlovsky, L., Kaufer, D., Friedman, A., Glick, D., Ben-Arie, N. & Soreq, H., 18 Jan 2002, In: Science. 295, 5554, p. 508-512 5 p.

Research output: Contribution to journal › Article › peer-review

208 Scopus citations

2001

Induced neuronal differentiation of human embryonic stem cells

Schuldiner, M., Eiges, R., Eden, A., Yanuka, O., Itskovitz-Eldor, J., Goldstein, R. S. & Benvenisty, N., 21 Sep 2001, In: Brain Research. 913, 2, p. 201-205 5 p.

Research output: Contribution to journal › Article › peer-review

373 Scopus citations

Interactions between Adaptor Protein-1 of the Clathrin Coat and Microtubules via Type 1a Microtubule-associated Proteins

Orzech, E., Livshits, L., Leyt, J., Okhrimenko, H., Reich, V., Cohen, S., Weiss, A., Melamed-Book, N., Lebendiker, M., Altschuler, Y. & Aroeti, B., 17 Aug 2001, In: Journal of Biological Chemistry. 276, 33, p. 31340-31348 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Nato3 is an evolutionarily conserved bHLH transcription factor expressed in the CNS of Drosophila and mouse

Segev, E., Halachmi, N., Salzberg, A. & Ben-Arie, N., 2001, In: Mechanisms of Development. 106, 1-2, p. 197-202 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

Spatial and temporal expression pattern of Runx3 (Aml2) and Runx1 (Aml1) indicates non-redundant functions during mouse embryogenesis

Levanon, D., Brenner, O., Negreanu, V., Bettoun, D., Woolf, E., Eilam, R., Lotem, J., Gat, U., Otto, F., Speck, N. & Groner, Y., 2001, In: Mechanisms of Development. 109, 2, p. 413-417 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

172 Scopus citations

2000

Apical and basolateral endocytic pathways of MDCK cells meet in acidic common endosomes distinct from a nearly-neutral apical recycling endosome

Wang, E., Brown, P. S., Aroeti, B., Chapin, S. J., Mostov, K. E. & Dunn, K. W., 2000, In: Traffic. 1, 6, p. 480-493 14 p.

Research output: Contribution to journal › Article › peer-review

126 Scopus citations

Autoregulation and multiple enhancers control Math1 expression in the developing nervous system

Helms, A. W., Abney, A. L., Ben-Arie, N., Zoghbi, H. Y. & Johnson, J. E., Mar 2000, In: Journal of Embryology and Experimental Morphology. 127, 6, p. 1185-1196 12 p.

Research output: Contribution to journal › Article › peer-review

258 Scopus citations

Definition of distinct compartments in polarized madin-darby canine kidney (MDCK) cells for membrane-volume sorting, polarized sorting and apical recycling

Brown, P. S., Wang, E., Aroeti, B., Chapin, S. J., Mostov, K. E. & Dunn, K. W., 2000, In: Traffic. 1, 2, p. 124-140 17 p.

Research output: Contribution to journal › Article › peer-review

146 Scopus citations

Differentiation of Human Embryonic Stem Cells into Embryoid Bodies Comprising the Three Embryonic Germ Layers

Itskovitz-Eldor, J., Schuldiner, M., Karsenti, D., Eden, A., Yanuka, O., Amit, M., Soreq, H. & Benvenisty, N., Feb 2000, In: Molecular Medicine. 6, 2, p. 88-95 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1252 Scopus citations

Functional conservation of atonal and Math1 in the CNS and PNS

Ben-Arie, N., Hassan, B. A., Bermingham, N. A., Malicki, D. M., Armstrong, D., Matzuk, M., Bellen, H. J. & Zoghbi, H. Y., 2000, In: Journal of Embryology and Experimental Morphology. 127, 5, p. 1039-1048 10 p.

Research output: Contribution to journal › Article › peer-review

229 Scopus citations

Interactions between the exocytic and endocytic pathways in polarized Madin-Darby canine kidney cells

Orzech, E., Cohen, S., Weiss, A. & Aroeti, B., 19 May 2000, In: Journal of Biological Chemistry. 275, 20, p. 15207-15219 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

66 Scopus citations

1999

Interactions of the AP-1 Golgi adaptor with the polymeric immunoglobulin receptor and their possible role in mediating brefeldin A-sensitive basolateral targeting from the trans-Golgi network

Orzech, E., Schlessinger, K., Weiss, A., Okamoto, C. T. & Aroeti, B., 22 Jan 1999, In: Journal of Biological Chemistry. 274, 4, p. 2201-2215 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

40 Scopus citations

Involvement of branched-chain amino acid aminotransferase (Bcat1/Eca39) in apoptosis

Eden, A. & Benvenisty, N., 27 Aug 1999, In: FEBS Letters. 457, 2, p. 255-261 7 p.

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Math 1: An essential gene for the generation of inner ear hair cells

Bermingham, N. A., Hassan, B. A., Price, S. D., Vollrath, M. A., Ben-Arie, N., Eatock, R. A., Bellen, H. J., Lysakowski, A. & Zoghbi, H. Y., 11 Jun 1999, In: Science. 284, 5421, p. 1837-1841 5 p.

Research output: Contribution to journal › Article › peer-review