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Carlos Manuel Caldas

    1992 …2026

    Research activity per year

    Personal profile

    Expertise related to UN Sustainable Development Goals

    In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

    1. SDG 3 - Good Health and Well-being
      SDG 3 Good Health and Well-being
    2. SDG 9 - Industry, Innovation, and Infrastructure
      SDG 9 Industry, Innovation, and Infrastructure
    3. SDG 17 - Partnerships for the Goals
      SDG 17 Partnerships for the Goals

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    Collaborations and top research areas from the last five years

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    • AI-predicted spatial transcriptomics unlocks breast cancer biomarkers from pathology

      Shulman, E. D., Campagnolo, E. M., Lodha, R., Chung, Y., Stemmer, A., Cantore, T., Ru, B., Chang, T. G., Biswas, S., Dhruba, S. R., Patiyal, S., Patkar, S., Wang, A., Barman, R. K., Wang, C., Paul, R., Kalisetty, S. C., Hu, T., Nasrallah, M. P. & Patrick, E. & 14 others, Yang, J., Yuan, Y., Sargsyan, K., Plotkin, A., Rajagopal, P. S., Sammut, S. J., Lipkowitz, S., Jiang, P., Caldas, C., Knott, S. R. V., Aldape, K., Lee, J. S., Hoang, D. T. & Ruppin, E., 2026, (Accepted/In press) In: Cell.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      2 Scopus citations

    • A multi-ancestry genome-wide study of tamoxifen metabolism and breast cancer recurrence

      Khor, C. C., Ong, W. S., Lim, E. H., Chatelut, E., Chen, S., Muerdter, T. E., Abraham, J. E., Sutiman, N., Lim, J. S. L., Lee, S. S., Arellano, C., Li, Z., Sim, K. S., Eccles, D. M., Tapper, W. J., Maishman, T., Zgheib, N. K., Winter, S., Ganchev, B. & Dorling, L. & 29 others, Guo, Q., Caldas, C., Earl, H. M., Hiller, L., Dunn, J., Ng, R. C. H., Yap, Y. S., Wong, M., Wong, F. Y., Wong, N. S., Ang, P. C. S., Dent, R., Krippl, P., Langsenlehner, U., Langsenlehner, T., Tfayli, A., Schaeffeler, E., Eichelbaum, M., Hamann, U., Fasching, P. A., Beckmann, M. W., Dalenc, F., White-Koning, M., Brauch, H. B., Schroth, W., Renner, W., Schwab, M., Thomas, F. & Chowbay, B., Dec 2026, In: npj Breast Cancer. 12, 1, 71.

      Research output: Contribution to journal › Article › peer-review

      Open Access

    • Compartment-specific tumor-infiltrating immune cells and prognosis in breast cancer

      Bernstein, A. J., Keeman, R., Hurson, A. N., Blows, F. M., Bolla, M. K., Miller, J. L., Milne, R. L., Horlings, H., van den Broek, A. J., Bodelon, C., Hodge, J. M., Patel, A. V., Teras, L. R., Canzian, F., Kaaks, R., Brenner, H., Schöttker, B., Behrens, S., Chang-Claude, J. & Maurer, T. & 45 others, Obi, N., Couch, F. J., Ali, H. R., Caldas, C., Andrulis, I., Glendon, G., Mulligan, A. M., Mesker, W., Jager, A., Heemskerk-Gerritsen, A., Devilee, P., Lawrence, S. M., Lissowska, J., Mutreja, K., Ahearn, T., Chanock, S., Duggan, M. A., Eccles, D., Jones, J. L., Tapper, W., Hollestelle, A., Hooning, M., Martens, J., van Deurzen, C. H. M., Cox, A., Cross, S. S., Hartman, M., Li, J., Putti, T. C., Hamann, U., Rashid, M., Jakubowska, A., Camp, N., Cessna, M. H., Berrington de Gonzalez, A., Bialkowska, K., Gronwald, J., Lubiński, J., Yadav, S., Lio, P., Easton, D. F., Abubakar, M., Garcia-Closas, M., Pharoah, P. D. P. & Schmidt, M. K., 20 Feb 2026, In: iScience. 29, 2, 114759.

      Research output: Contribution to journal › Article › peer-review

      Open Access

    • Enhanced prediction of breast cancer patient response to chemotherapy by integrating deconvolved expression patterns of immune, stromal and tumor cells

      Dhruba, S. R., Sahni, S., Wang, B., Wu, D., Rajagopal, P. S., Schmidt, Y., Shulman, E. D., Sinha, S., Sammut, S. J., Caldas, C., Wang, K. & Ruppin, E., 31 Mar 2026, In: Cancer Letters. 641, 218101.

      Research output: Contribution to journal › Article › peer-review

      Open Access

    • Evaluating progesterone receptor agonist megestrol plus letrozole for women with early-stage estrogen-receptor-positive breast cancer: the window-of-opportunity, randomized, phase 2b, PIONEER trial

      Burrell, R. A., Kumar, S., Provenzano, E., Pike, C., Dayimu, A., McIntosh, S. A., Pitsinis, V., King, P., Elsberger, B., Govindarajulu, S., Satherley, L., Hadad, S., Schmid, P., Agrawal, A., Akpuluma, B., Bell, S., Benson, J. R., Caldas, C., Cheeseman, D. & Chernukhin, I. & 8 others, Forouhi, P., Gulsen, T., Kleidi, E., Pinilla, K., Qian, W., Abraham, J. E., Carroll, J. S. & Baird, R. D., Jan 2026, In: Nature Cancer. 7, 1, p. 194-206 13 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1 Scopus citations
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