Abstract
The use of 2‐nitro‐4‐methoxy‐phenylsulfenyl‐(I) as an amino protecting group which is extremely sensitive towards electrophilic attack in the synthesis of amino penicillins (amino‐penicillin and DL‐α‐amino‐benzylpenicillin) is described. Synthesis of few protected dipeptides (2‐nitro‐4‐methoxyphenylsulfenyl‐L‐phenylalanyl‐L‐valine, 2‐nitro‐4‐methoxyphenylsulfenyl‐L‐phenylalanyl‐L‐phenylalanine and 2‐nitro‐4‐methoxyphenylsulfenyl‐L‐valyl‐L‐phenylalanine) demonstrates the use of the protecting group in peptide synthesis.
Original language | English |
---|---|
Pages (from-to) | 231-236 |
Number of pages | 6 |
Journal | Israel Journal of Chemistry |
Volume | 5 |
Issue number | 5 |
DOIs | |
State | Published - 1967 |