TY - JOUR
T1 - 4D Printing of Shape Memory-Based Personalized Endoluminal Medical Devices
AU - Zarek, Matt
AU - Mansour, Nicola
AU - Shapira, Shir
AU - Cohn, Daniel
N1 - Publisher Copyright:
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
PY - 2017/1/1
Y1 - 2017/1/1
N2 - The convergence of additive manufacturing and shape-morphing materials is promising for the advancement of personalized medical devices. The capability to transform 3D objects from one shape to another, right off the print bed, is known as 4D printing. Shape memory thermosets can be tailored to have a range of thermomechanical properties favorable to medical devices, but processing them is a challenge because they are insoluble and do not flow at any temperature. This study presents here a strategy to capitalize on a series of medical imaging modalities to construct a printable shape memory endoluminal device, exemplified by a tracheal stent. A methacrylated polycaprolactone precursor with a molecular weight of 10 000 g mol−1 is printed with a UV-LED stereolithography printer based on anatomical data. This approach converges with the zeitgeist of personalized medicine and it is anticipated that it will broadly expand the application of shape memory-exhibiting biomedical devices to myriad clinical indications. (Figure presented.).
AB - The convergence of additive manufacturing and shape-morphing materials is promising for the advancement of personalized medical devices. The capability to transform 3D objects from one shape to another, right off the print bed, is known as 4D printing. Shape memory thermosets can be tailored to have a range of thermomechanical properties favorable to medical devices, but processing them is a challenge because they are insoluble and do not flow at any temperature. This study presents here a strategy to capitalize on a series of medical imaging modalities to construct a printable shape memory endoluminal device, exemplified by a tracheal stent. A methacrylated polycaprolactone precursor with a molecular weight of 10 000 g mol−1 is printed with a UV-LED stereolithography printer based on anatomical data. This approach converges with the zeitgeist of personalized medicine and it is anticipated that it will broadly expand the application of shape memory-exhibiting biomedical devices to myriad clinical indications. (Figure presented.).
KW - 4D printing
KW - biomedical devices
KW - personalized medicine
KW - shape-memory polymers
UR - http://www.scopus.com/inward/record.url?scp=85006339739&partnerID=8YFLogxK
U2 - 10.1002/marc.201600628
DO - 10.1002/marc.201600628
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C2 - 27918636
AN - SCOPUS:85006339739
SN - 1022-1336
VL - 38
JO - Macromolecular Rapid Communications
JF - Macromolecular Rapid Communications
IS - 2
M1 - 1600628
ER -