4S oop RNA is a leader sequence for the immunity-establishment transcription in coliphage λ

A. Honigman; S. L. Hu; R. Chase; W. Szybalski

doi:10.1038/262112a0

4S oop RNA is a leader sequence for the immunity-establishment transcription in coliphage λ

A. Honigman^*
, S. L. Hu
, R. Chase
, W. Szybalski

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

oop RNA, which is initiated at the p_o promoter and is 81 nucleotides long, can function as a leader sequence for the λ immunity establishment transcription, previously believed to originate at a special promoter p_re located in the y region. Thus, oop RNA seems to have a dual role, either favouring the lytic cycle as a primer for the initiation of λ DNA replication, or leading to the establishment of lysogeny when elongated into the imm transcript, which directs synthesis of the repressor.

Original language	English
Pages (from-to)	112-116
Number of pages	5
Journal	Nature
Volume	262
Issue number	5564
DOIs	https://doi.org/10.1038/262112a0
State	Published - 1976
Externally published	Yes

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title = "4S oop RNA is a leader sequence for the immunity-establishment transcription in coliphage λ",

abstract = "oop RNA, which is initiated at the po promoter and is 81 nucleotides long, can function as a leader sequence for the λ immunity establishment transcription, previously believed to originate at a special promoter pre located in the y region. Thus, oop RNA seems to have a dual role, either favouring the lytic cycle as a primer for the initiation of λ DNA replication, or leading to the establishment of lysogeny when elongated into the imm transcript, which directs synthesis of the repressor.",

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AU - Honigman, A.

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AU - Chase, R.

AU - Szybalski, W.

PY - 1976

Y1 - 1976

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AB - oop RNA, which is initiated at the po promoter and is 81 nucleotides long, can function as a leader sequence for the λ immunity establishment transcription, previously believed to originate at a special promoter pre located in the y region. Thus, oop RNA seems to have a dual role, either favouring the lytic cycle as a primer for the initiation of λ DNA replication, or leading to the establishment of lysogeny when elongated into the imm transcript, which directs synthesis of the repressor.

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4S oop RNA is a leader sequence for the immunity-establishment transcription in coliphage λ

Abstract

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