A 2-year mean follow-up of oral appliance therapy for severe obstructive sleep apnea: A cohort study

Y. Haviv*, G. Bachar, D. J. Aframian, G. Almoznino, E. Michaeli, R. Benoliel

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    19 Scopus citations


    Objective: Oral appliances for treating severe obstructive sleep apnea (OSA) are recommended for patients who failed to comply with continuous positive airway pressure (CPAP) treatment. The objective of this study was to evaluate medium long-term outcome and success rates of oral appliances in patients with severe OSA. Methods: In a retrospective study, 52 OSA patients with an apnea-hypopnea index (AHI) ≥40, who did not tolerate CPAP treatment, were enrolled and fitted with a modified Herbst oral appliance. A 2-year mean follow-up including a second somnography was conducted in 36 of the patients. Results: A significant reduction (P < 0.0001) in the AHI was demonstrated between the initial somnography (55.25 ± 10.79,) and the followed one (17.74 ± 11.0, n = 36). Overall, 57.7% of total study subjects (n = 52) and 63.9% (n = 36) that had sequential sonmogarphy continued using the device. The reduction in AHI in the user group was 42.4 ± 3.1 (n = 23), which was significantly higher (P = 0.013) than in the non-user group (28.9 ± 17.2; n = 13). Moreover, 53% (n = 19) reached AHI of <15. Conclusions: Oral appliances were found to be successful for treating for severe OSA after first-line treatment had failed.

    Original languageAmerican English
    Pages (from-to)386-392
    Number of pages7
    JournalOral Diseases
    Issue number3
    StatePublished - 1 Apr 2015

    Bibliographical note

    Publisher Copyright:
    © 2015 John Wiley & Sons A/S.


    • Apnea hypopnea index
    • Continuous positive airway pressure
    • Dental appliance
    • Obstructive sleep apnea
    • Oral appliance


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