TY - JOUR
T1 - A 6-month study of the effects of 0.3% triclosan/copolymer dentifrice on dental implants
AU - Sreenivasan, Prem K.
AU - Vered, Yuval
AU - Zini, Avi
AU - Mann, Jonathan
AU - Kolog, Hilla
AU - Steinberg, Doron
AU - Zambon, Joseph J.
AU - Haraszthy, Violet I.
AU - Da Silva, Maike P.
AU - De Vizio, William
PY - 2011/1
Y1 - 2011/1
N2 - Aim: Supportive therapy to maintain dental implants is increasingly important. This study examined the effect of a 0.3% triclosan/2% copolymer dentifrice on oral biofilms and gingival inflammation (GI) on dental implants and peri-implant tissues. Materials and Methods: One hundred and twenty adults with a dental implant and contra-lateral tooth were enrolled in this 6 month, double-blind, two-treatment, parallel group study. Sixty subjects were randomly assigned to a triclosan/copolymer dentifrice test group and 60 subjects to a fluoride dentifrice control group and instructed to brush twice daily for 6 months. At baseline, 3, and 6 months, a calibrated dentist assessed dental plaque, GI and collected supragingival dental plaque for microbiological analysis. Results: Subjects in the triclosan/copolymer group demonstrated significantly lower levels of dental plaque, gingivitis, and bleeding on probing at 3 and 6 months at both the implant and contra-lateral tooth compared with the fluoride group (p<0.05). There were significantly fewer Gram-negative anaerobes in the triclosan/copolymer group (p<0.05) including >90% reductions in Aggregatibacter actinomycetemcomitans, Campylobacter rectus, Eubacterium saburreum, Fusobacterium nucleatum, Porphyromonas gingivalis, Prevotella melaninogenica, Solobacterium moorei, and Tannerella forsythia. Conclusions: Twice daily use of a triclosan/copolymer dentifrice may enhance dental implant maintenance by reducing dental plaque and GI.
AB - Aim: Supportive therapy to maintain dental implants is increasingly important. This study examined the effect of a 0.3% triclosan/2% copolymer dentifrice on oral biofilms and gingival inflammation (GI) on dental implants and peri-implant tissues. Materials and Methods: One hundred and twenty adults with a dental implant and contra-lateral tooth were enrolled in this 6 month, double-blind, two-treatment, parallel group study. Sixty subjects were randomly assigned to a triclosan/copolymer dentifrice test group and 60 subjects to a fluoride dentifrice control group and instructed to brush twice daily for 6 months. At baseline, 3, and 6 months, a calibrated dentist assessed dental plaque, GI and collected supragingival dental plaque for microbiological analysis. Results: Subjects in the triclosan/copolymer group demonstrated significantly lower levels of dental plaque, gingivitis, and bleeding on probing at 3 and 6 months at both the implant and contra-lateral tooth compared with the fluoride group (p<0.05). There were significantly fewer Gram-negative anaerobes in the triclosan/copolymer group (p<0.05) including >90% reductions in Aggregatibacter actinomycetemcomitans, Campylobacter rectus, Eubacterium saburreum, Fusobacterium nucleatum, Porphyromonas gingivalis, Prevotella melaninogenica, Solobacterium moorei, and Tannerella forsythia. Conclusions: Twice daily use of a triclosan/copolymer dentifrice may enhance dental implant maintenance by reducing dental plaque and GI.
KW - bacteria
KW - biofilm
KW - dental implant
KW - gingivitis
KW - triclosan
UR - http://www.scopus.com/inward/record.url?scp=78650346141&partnerID=8YFLogxK
U2 - 10.1111/j.1600-051X.2010.01617.x
DO - 10.1111/j.1600-051X.2010.01617.x
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C2 - 20831669
AN - SCOPUS:78650346141
SN - 0303-6979
VL - 38
SP - 33
EP - 42
JO - Journal of Clinical Periodontology
JF - Journal of Clinical Periodontology
IS - 1
ER -