TY - JOUR
T1 - A Case for Distributed Control of Local Stem Cell Behavior in Plants
AU - Rahni, Ramin
AU - Efroni, Idan
AU - Birnbaum, Kenneth D.
N1 - Publisher Copyright:
© 2016 Elsevier Inc.
PY - 2016/9/26
Y1 - 2016/9/26
N2 - The root meristem has a centrally located group of mitotically quiescent cells, to which current models assign a stem cell organizer function. However, evidence is emerging for decentralized control of stem cell activity, whereby self-renewing behavior emerges from the lack of cell displacement at the border of opposing differentiation gradients. We term this a “stagnation” model due to its reliance on passive mechanics. The position of stem cells is established by two opposing axes that reciprocally control each other's differentiation. Such broad tissue organization programs would allow plants, like some animal systems, to rapidly reconstitute stem cells from non-stem-cell tissues.
AB - The root meristem has a centrally located group of mitotically quiescent cells, to which current models assign a stem cell organizer function. However, evidence is emerging for decentralized control of stem cell activity, whereby self-renewing behavior emerges from the lack of cell displacement at the border of opposing differentiation gradients. We term this a “stagnation” model due to its reliance on passive mechanics. The position of stem cells is established by two opposing axes that reciprocally control each other's differentiation. Such broad tissue organization programs would allow plants, like some animal systems, to rapidly reconstitute stem cells from non-stem-cell tissues.
UR - http://www.scopus.com/inward/record.url?scp=84991810107&partnerID=8YFLogxK
U2 - 10.1016/j.devcel.2016.08.015
DO - 10.1016/j.devcel.2016.08.015
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C2 - 27676436
AN - SCOPUS:84991810107
SN - 1534-5807
VL - 38
SP - 635
EP - 642
JO - Developmental Cell
JF - Developmental Cell
IS - 6
ER -