A Distinct Transcriptional Program in Human CAR T Cells Bearing the 4-1BB Signaling Domain Revealed by scRNA-Seq

  • Angela C. Boroughs
  • , Rebecca C. Larson
  • , Nemanja D. Marjanovic
  • , Kirk Gosik
  • , Ana P. Castano
  • , Caroline B.M. Porter
  • , Selena J. Lorrey
  • , Orr Ashenberg
  • , Livnat Jerby
  • , Matan Hofree
  • , Gabriela Smith-Rosario
  • , Robert Morris
  • , Joshua Gould
  • , Lauren S. Riley
  • , Trisha R. Berger
  • , Samantha J. Riesenfeld
  • , Orit Rozenblatt-Rosen
  • , Bryan D. Choi
  • , Aviv Regev*
  • , Marcela V. Maus*
  • *Corresponding author for this work

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82 Scopus citations

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Medicine and Dentistry

Immunology and Microbiology

Biochemistry, Genetics and Molecular Biology