The response of plants to environmental cues, particularly stresses, involves the coordinated induction or repression of gene expression. In a previous study, we developed a bioinformatics approach to analyze the mutual expression pattern of genes encoding transcription factors and metabolic enzymes upon exposure of Arabidopsis plants to abiotic and biotic stresses. The analysis resulted in three gene clusters, each displaying a unique expression pattern. In the present addendum, we address the composition of each of these three clusters in regard to the functional identity of their encoded proteins as enzymes or transcription factors.
Bibliographical noteFunding Information:
tunity to examine small, highly coordinated networks of genes This research was supported by grants from The Israel Science encoding enzymes and TFs and possibly assess their biological Foundation (grant No. 764/07) and from the United States– functions and regulatory interplay. As an example of this issue, Israel Binational Agricultural Research and Development Fund we analyzed clique number 70, which contains 24 genes encoding (grant no. IS–3331–02). GG is an incumbent of the Bronfman five TFs and 19 enzymes (see Supplemental Table 2, reference 1). Chair of Plant Science at the Weizmann Institute of Science.