Abstract
A method is proposed for the evaluation of the cell cycle time of in vivo steady state populations. It requires only an accurate estimation of either the labelling index or the mitotic index and an approximate evaluation of the period between the initiation of the S phase and the completion of mitosis. The method proposed takes into accoimt the fact that the cell cycle is non‐deterministic, the angle at which cells divide and the effect of cell extrusion from the basal layer, plus the fact that the cells can only be extruded when in certain phases of the cell cycle. Limitations of other methods recently reported are discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 1-6 |
| Number of pages | 6 |
| Journal | British Journal of Dermatology |
| Volume | 107 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jul 1982 |