TY - JOUR
T1 - A kinetic model for release of electrolytes from w/o/w multiple emulsions
AU - Magdassi, Shlomo
AU - Garti, Nissim
N1 - Funding Information:
The authors wish to acknowledge Teva Pharmaceuticals, Israel, for their financial support.
PY - 1986
Y1 - 1986
N2 - The release of electrolytes from W/O/W emulsions was studied. A significant difference was observed in the release of sodium chloride and organic ion (ephedrine hydrochloride). The rate of release decreased with the increase of the initial concentration of the electrolyte. A kinetic model which is similar to the model for release of dispersed drugs from a polymeric matrix was found to be suitable for the release of electrolytes from multiple emulsions.
AB - The release of electrolytes from W/O/W emulsions was studied. A significant difference was observed in the release of sodium chloride and organic ion (ephedrine hydrochloride). The rate of release decreased with the increase of the initial concentration of the electrolyte. A kinetic model which is similar to the model for release of dispersed drugs from a polymeric matrix was found to be suitable for the release of electrolytes from multiple emulsions.
UR - http://www.scopus.com/inward/record.url?scp=0022510843&partnerID=8YFLogxK
U2 - 10.1016/0168-3659(86)90098-2
DO - 10.1016/0168-3659(86)90098-2
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AN - SCOPUS:0022510843
SN - 0168-3659
VL - 3
SP - 273
EP - 277
JO - Journal of Controlled Release
JF - Journal of Controlled Release
IS - 1-4
ER -