TY - JOUR
T1 - A mimic of superoxide dismutase activity protects Chlorella sorokiniana against the toxicity of sulfite
AU - Rabinowitch, Haim D.
AU - Rosen, Gerald M.
AU - Fridovich, Irwin
PY - 1989
Y1 - 1989
N2 - The spin-trapping agent 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) has been used to demonstrate the light-dependent production of O2 - by Chlorella sorokiniana. In the presence of SO3 = a light-dependent production of the sulfur trioxy anion radical (SO3 -.) could also be seen. A complex prepared by reacting desferrioxamine with MnO2, which catalyzes the dismutation of O2 -, protected the alga against the toxicity of sulfite. The data suggest that SO2 toxicity is at least partially due to the effects of sulfoxy-free radicals generated by the oxidation of SO3 = by O2 -.
AB - The spin-trapping agent 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) has been used to demonstrate the light-dependent production of O2 - by Chlorella sorokiniana. In the presence of SO3 = a light-dependent production of the sulfur trioxy anion radical (SO3 -.) could also be seen. A complex prepared by reacting desferrioxamine with MnO2, which catalyzes the dismutation of O2 -, protected the alga against the toxicity of sulfite. The data suggest that SO2 toxicity is at least partially due to the effects of sulfoxy-free radicals generated by the oxidation of SO3 = by O2 -.
UR - http://www.scopus.com/inward/record.url?scp=0024537070&partnerID=8YFLogxK
U2 - 10.1016/0891-5849(89)90158-5
DO - 10.1016/0891-5849(89)90158-5
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C2 - 2536342
AN - SCOPUS:0024537070
SN - 0891-5849
VL - 6
SP - 45
EP - 48
JO - Free Radical Biology and Medicine
JF - Free Radical Biology and Medicine
IS - 1
ER -