A nanoscale optical biosensor based on peptide encapsulated SWCNTs for detection of acetic acid in the gaseous phase

Vlad Shumeiko, Einav Malach, Yael Helman, Yossi Paltiel, Gili Bisker, Zvi Hayouka*, Oded Shoseyov

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

30 Scopus citations

Abstract

Biosensors play a key role in almost every field of human activity – ranging from biomedical diagnosis and point-of-care health monitoring to environmental monitoring and forensics. Single-walled carbon nanotubes (SWCNTs) are one of the most promising materials for near-infrared (NIR) fluorescence-based biosensing. Herein, we develop a reusable, drop-casted, real-time optical biosensor based on peptide-encapsulated SWCNTs for the detection of low concentrations of acetic acid in the air, at room temperature. While detection of NIR signal usually requires expensive and bulky equipment, here we use the (6,5) SWCNTs chirality whose peak fluorescence lies within the range of 970 nm – 1050 nm, enabling the usage of low cost and compact silicon-based detectors. We demonstrate the detection of wine spoilage based on excess gaseous acetic acid using peptide-wrapped SWCNT sensors down to 0.05% (v/v) acetic acid concentrations. Our results open new avenues for gas phase detection using NIR fluorescent SWCNT nanosensors.

Original languageAmerican English
Article number128832
JournalSensors and Actuators, B: Chemical
Volume327
DOIs
StatePublished - 15 Jan 2021

Bibliographical note

Funding Information:
G.B. acknowledges the support of the Zuckerman STEM Leadership Program , and The Israel Science Foundation (grant No. 456/18 ).

Publisher Copyright:
© 2020 Elsevier B.V.

Keywords

  • Optical biosensors
  • acetic acid
  • carbon nanotubes
  • spoilage
  • wine

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