TY - JOUR
T1 - A new technique for the analysis of background and evoked EEG activity
T2 - Time and amplitude distributions of the EEG deflections
AU - Rodionov, V.
AU - Goodman, C.
AU - Fisher, L.
AU - Rosenstein, G. Z.
AU - Sohmer, H.
PY - 2002
Y1 - 2002
N2 - Objectives: The EEG during background activity and that evoked in response to sensory stimuli (evoked potential, EP) has traditionally been studied by averaging and by frequency analysis. These obscure trial to trial variability. A new analysis technique is presented here which leads to single trial analysis and to insight into the mechanisms of EP generation. Methods: This technique is based on the identification of the EEG deflections recorded on the scalp before (background) and immediately after visual stimuli. A statistical description of the time and amplitude distributions of these deflections is defined and leads to the differentiation between background and evoked activity. Results: In response to stimuli, the time and amplitude of ongoing deflections (background) are re-organized (time locking) and amplified, generating the EP. Not all stimulus trials are accompanied by an appropriate response. Separate analysis of those single trials that do contain a response deflection provides information on the exact timing, variability, amplitude, etc., of those EEG deflections which contribute to the EP. Conclusions: New EEG analysis techniques are described which provide single trial EP analysis and insight into mechanisms of EP generation.
AB - Objectives: The EEG during background activity and that evoked in response to sensory stimuli (evoked potential, EP) has traditionally been studied by averaging and by frequency analysis. These obscure trial to trial variability. A new analysis technique is presented here which leads to single trial analysis and to insight into the mechanisms of EP generation. Methods: This technique is based on the identification of the EEG deflections recorded on the scalp before (background) and immediately after visual stimuli. A statistical description of the time and amplitude distributions of these deflections is defined and leads to the differentiation between background and evoked activity. Results: In response to stimuli, the time and amplitude of ongoing deflections (background) are re-organized (time locking) and amplified, generating the EP. Not all stimulus trials are accompanied by an appropriate response. Separate analysis of those single trials that do contain a response deflection provides information on the exact timing, variability, amplitude, etc., of those EEG deflections which contribute to the EP. Conclusions: New EEG analysis techniques are described which provide single trial EP analysis and insight into mechanisms of EP generation.
KW - Amplification
KW - Electroencephalography
KW - Evoked potential
KW - Single trial
KW - Time locking
KW - Visual
UR - http://www.scopus.com/inward/record.url?scp=0036346047&partnerID=8YFLogxK
U2 - 10.1016/S1388-2457(02)00199-2
DO - 10.1016/S1388-2457(02)00199-2
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C2 - 12169322
AN - SCOPUS:0036346047
SN - 1388-2457
VL - 113
SP - 1412
EP - 1422
JO - Clinical Neurophysiology
JF - Clinical Neurophysiology
IS - 9
ER -