Abstract
A one pot, high yield synthesis of depsipeptides is described involving room temperature condensation of hindered substrates (N-Boc amino acids and benzyl α-hydroxy esters) in the presence of DCC and a dialkylaminopyridine. In this manner previously inaccessible depsipeptides were prepared.
Original language | English |
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Pages (from-to) | 3811-3814 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 20 |
Issue number | 40 |
DOIs | |
State | Published - 1979 |