A sensitive plaque inhibition technique for assay of antibodies to influenza virus: Use to detect previous antigenic priming with influenza viruses

Z. Zakay-Rones*, E. Margalith, R. Levy, E. Katz

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Plaque reduction test performed in MDCK cells was found to be a more sensitive assay than hemagglutination inhibition, for revealing previous immunological experience with influenza A virus in the population. Based on the preimmunization antibody levels, determined by plaque reduction tests, it was possible to distinguish between previously primed and unprimed subjects among vaccinees.

Original languageEnglish
Pages (from-to)355-360
Number of pages6
JournalJournal of Virological Methods
Volume1
Issue number6
DOIs
StatePublished - 1980

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