A simple method for determining whether absorption and elimination rate constants are equal in the one-compartment open model with first-order processes

Meir Bialer

doi:10.1007/BF01059453

A simple method for determining whether absorption and elimination rate constants are equal in the one-compartment open model with first-order processes

Meir Bialer^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

A simple method is presented by which one may determine if the absorption and the elimination rate constants are equal (in the one-compartment body model) using only plasma drug data. This method suggests the pertinent equation to calculate the relevent pharmacokinetic parameters.

Original language	English
Pages (from-to)	111-113
Number of pages	3
Journal	Journal of Pharmacokinetics and Biopharmaceutics
Volume	8
Issue number	1
DOIs	https://doi.org/10.1007/BF01059453
State	Published - Feb 1980
Externally published	Yes

Keywords

equal absorption and elimination rate constants
first-order process
one-compartment body model

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10.1007/BF01059453

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abstract = "A simple method is presented by which one may determine if the absorption and the elimination rate constants are equal (in the one-compartment body model) using only plasma drug data. This method suggests the pertinent equation to calculate the relevent pharmacokinetic parameters.",

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KW - equal absorption and elimination rate constants

KW - first-order process

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A simple method for determining whether absorption and elimination rate constants are equal in the one-compartment open model with first-order processes

Abstract

Keywords

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