Abstract
It's in the bond: The cleavage of C H bonds by two related oxoiron(IV) complexes shows a range of kinetic isotope effect (KIE) values that exhibit an unusual dependence on the C H bond strength. Large nonclassical KIEs are observed for bond strengths below 93 kcal mol-1, while semiclassical values are found above this value (see graph, DHA=9,10- dihydroanthracene). This nonintuitive behavior can be rationalized by invoking a two-state reactivity model.
Original language | English |
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Pages (from-to) | 1291-1295 |
Number of pages | 5 |
Journal | Angewandte Chemie - International Edition |
Volume | 48 |
Issue number | 7 |
DOIs | |
State | Published - 2 Feb 2009 |
Keywords
- Bioinorganic chemistry
- Iron
- Isotope effects
- Isotopic labeling
- Two-state reactivity