TY - JOUR
T1 - A Vibrational Analysis of Rhodopsin and Bacteriorhodopsin Chromophore Analogues
T2 - Resonance Raman and Infrared Spectroscopy of Chemically Modified Retinals and Schiff Bases
AU - Lewis, Aaron
AU - Lemley, Ann T.
AU - Cookingham, Robert E.
PY - 1978
Y1 - 1978
N2 - Resonance Raman spectroscopy has been used to study chemically modified retinal analogues involving chain substitutions, ring substitutions, or Schiff-base linkages. In addition, retinal fragments and fully deuterated retinals were investigated, and infrared spectra of the four isomers of retinal were obtained. Low-frequency resonance Raman spectra are also reported for all of the isomers of retinal, for the protonated and unprotonated Schiff bases of frans-retinal, for β-ionone, and for trans-3-dehydroretinal. Band assignments were made to specific vibrational motions, and these assignments have led to a detailed understanding of the spectral features observed in the resonance Raman spectra of the retinylidene chromophore in rhodopsin and bacteriorhodopsin.
AB - Resonance Raman spectroscopy has been used to study chemically modified retinal analogues involving chain substitutions, ring substitutions, or Schiff-base linkages. In addition, retinal fragments and fully deuterated retinals were investigated, and infrared spectra of the four isomers of retinal were obtained. Low-frequency resonance Raman spectra are also reported for all of the isomers of retinal, for the protonated and unprotonated Schiff bases of frans-retinal, for β-ionone, and for trans-3-dehydroretinal. Band assignments were made to specific vibrational motions, and these assignments have led to a detailed understanding of the spectral features observed in the resonance Raman spectra of the retinylidene chromophore in rhodopsin and bacteriorhodopsin.
UR - http://www.scopus.com/inward/record.url?scp=0018280685&partnerID=8YFLogxK
U2 - 10.1021/bi00615a017
DO - 10.1021/bi00615a017
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C2 - 728379
AN - SCOPUS:0018280685
SN - 0006-2960
VL - 17
SP - 4699
EP - 4711
JO - Biochemistry
JF - Biochemistry
IS - 22
ER -