A virus spotlighted by an autonomous DNA machine

Yossi Weizmann; Moritz K. Beissenhirtz; Zoya Cheglakov; Roni Nowarski; Moshe Kotler; Itamar Willner

doi:10.1002/anie.200602754

A virus spotlighted by an autonomous DNA machine

Yossi Weizmann^*
, Moritz K. Beissenhirtz
, Zoya Cheglakov
, Roni Nowarski
, Moshe Kotler
, Itamar Willner

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

251 Scopus citations

Abstract

(Chemical Equation Presented) Highly sensitive: Analysis of viral DNA (M13 phage) is possible by using a DNA-based machine that is fueled by dNTPs and synthesizes DNAzyme reporter units. The DNAzymes mimic peroxidase and lead to a colorimetric or chemiluminescent readout of the analyzed DNA.

Original language	English
Pages (from-to)	7384-7388
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	45
Issue number	44
DOIs	https://doi.org/10.1002/anie.200602754
State	Published - 13 Nov 2006

Keywords

Biosensors
Chemiluminescence
DNA structures
DNAzymes
Enzymes

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10.1002/anie.200602754

Cite this

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AU - Willner, Itamar

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KW - Chemiluminescence

KW - DNA structures

KW - DNAzymes

KW - Enzymes

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A virus spotlighted by an autonomous DNA machine

Abstract

Keywords

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