Abnormal sterols in cholesterol-deficiency diseases cause secretory granule malformation and decreased membrane curvature

Keyphrases

• Malformation 100%
• Cholesterol 100%
• Sterols 100%
• Secretory Granules 100%
• Cause of Disease 100%
• Deficiency Diseases 100%
• Membrane Curvature 100%
• Cholesterol Deficiency 100%
• Granules 50%
• Lathosterolosis 33%
• DHCR7 33%
• Smith-Lemli-Opitz Syndrome 33%
• Mouse Model 16%
• Gene-deficient Mice 16%
• Lipids 16%
• Human Disease 16%
• Pancreas 16%
• Biosynthetic Pathway 16%
• Secretory Pathway 16%
• Adrenal Gland 16%
• Pituitary Gland 16%
• Acinar Cells 16%
• Bending Rigidity 16%
• Exocrine Pancreas 16%
• Functional Capacity 16%
• Intrinsic Curvature 16%
• Multiple Malformations 16%
• Artificial Membrane 16%
• Unesterified Cholesterol 16%
• Granule Biogenesis 16%
• Structural Capacity 16%
• Homozygous Recessive Characteristics 16%

Biochemistry, Genetics and Molecular Biology

• Precursor 100%
• Sterol 100%
• Membrane Curvature 100%
• Enzyme 50%
• Morphology 50%
• Rigidity 50%
• Lipid 50%
• Mouse Model 50%
• Anabolism 50%
• Secretory Pathway 50%
• Biogenesis 50%
• Functional Status 50%
• Artificial Membrane 50%