Acanthosis nigricans and truncal fat in overweight and obese children

Gal Dubnov-Raz*, Ram Weiss, Raanan Raz, Rakefet Arieli, Naama W. Constantini

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Background: Screening for acanthosis nigricans (AcN) in overweight children is repeatedly recommended. The significance of AcN, and its relation to central obesity in children, is unclear. Objective: To compare clinical and anthropometric parameters associated with adiposity, between overweight and obese children with and without AcN. Methods: One hundred and forty-nine overweight and obese children were screened for AcN. Height, weight, waist and hip circumferences, triceps skinfold thickness and segmental body fat amounts were measured. Results: Twenty-two (14.8 %) children had AcN. Children with AcN had greater height, weight, BMI, waist circumference, waist-to-height-ratio, triceps skinfold thickness, and total and truncal body fat percentage, compared to those without AcN. After adjustment for age and BMI, no adiposity measure was increased in children with AcN. Conclusion: Overweight and obese children with AcN basically have greater overall and central adiposity, than those without it. Adjusting for BMI, there is no evidence for increased abdominal fat in these children.

Original languageAmerican English
Pages (from-to)697-701
Number of pages5
JournalJournal of Pediatric Endocrinology and Metabolism
Issue number9-10
StatePublished - Oct 2011
Externally publishedYes


  • Abdominal obesity
  • Adiposity
  • Fat
  • Pediatrics


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