Acid-catalyzed hydration of alkynes in aqueous microemulsions

Zackaria Nairoukh, David Avnir, Jochanan Blum*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

Terminal aromatic alkynes are converted rapidly into ketones in a regioselective manner by treatment of their microemulsions with 0.33 M mineral acid between 80 and 140 °C. Internal and aliphatic acetylenes are likewise hydrated, but require longer reaction periods. The products are easily isolated from the reaction mixtures by phase separation. Replacement of H2O by D2O leads to the formation of trideuteriomethyl ketones.

Original languageAmerican English
Pages (from-to)430-432
Number of pages3
JournalChemSusChem
Volume6
Issue number3
DOIs
StatePublished - Mar 2013

Keywords

  • alkynes
  • green chemistry
  • homogeneous catalysis
  • microemulsions
  • synthetic methods

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