Abstract
An antimycotic agent was isolated from roots of alfalfa and further purified to yield a nonhemolytic, homogeneous compound (G2). This compound contained considerable activity against 10 medically important yeasts. MICs obtained by both agar and broth dilution methods ranged from 3 to 15 μg/ml. Compound G2 was fungicidal at a relatively concentration for nine different species of yeasts tested (minimum fungicidal concentrations ranged between 6 and 24 μg/ml. The considerable stability of compound G2 and its strong inhibitory and fungicidal activity against a broad range of yeasts suggest that after further development it might be useful as an active agent n the treatment of mycotic infections.
Original language | English |
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Pages (from-to) | 290-294 |
Number of pages | 5 |
Journal | Antimicrobial Agents and Chemotherapy |
Volume | 30 |
Issue number | 2 |
DOIs | |
State | Published - 1986 |
Externally published | Yes |