Acute myocardial infarction after bone marrow transplantation: An unsuspected late complication

Mooshie E. Gatt; D. Liebster; D. Leibowitz; Y. Matzner

doi:10.1007/s00277-002-0605-x

Acute myocardial infarction after bone marrow transplantation: An unsuspected late complication

Mooshie E. Gatt^*, D. Liebster, D. Leibowitz, Y. Matzner

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Acute myocardial infarction is a common disease rarely seen as a complication of bone marrow transplantation in young patients. We report on a 25-year-old patient 3.5 years after bone marrow transplantation who suffered an acute anterior wall myocardial infarction complicated by cardiogenic shock. The patient was treated with thrombolysis and emergent coronary angioplasty but died a few hours following admission. We suggest that the combination of low-dose chest irradiation and prolonged immunosuppression with graft-versus-host disease contributed to the development of the coronary artery disease in this patient. Though rarely encountered, physicians caring for young patients after bone marrow transplantation should be aware of potential ischemic complications.

Original language	American English
Pages (from-to)	136-138
Number of pages	3
Journal	Annals of Hematology
Volume	82
Issue number	2
DOIs	https://doi.org/10.1007/s00277-002-0605-x
State	Published - 1 Feb 2003
Externally published	Yes

Keywords

Bone marrow transplantation
Graft-versus-host disease
Myocardial infarction

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abstract = "Acute myocardial infarction is a common disease rarely seen as a complication of bone marrow transplantation in young patients. We report on a 25-year-old patient 3.5 years after bone marrow transplantation who suffered an acute anterior wall myocardial infarction complicated by cardiogenic shock. The patient was treated with thrombolysis and emergent coronary angioplasty but died a few hours following admission. We suggest that the combination of low-dose chest irradiation and prolonged immunosuppression with graft-versus-host disease contributed to the development of the coronary artery disease in this patient. Though rarely encountered, physicians caring for young patients after bone marrow transplantation should be aware of potential ischemic complications.",

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AU - Gatt, Mooshie E.

AU - Liebster, D.

AU - Leibowitz, D.

AU - Matzner, Y.

PY - 2003/2/1

Y1 - 2003/2/1

N2 - Acute myocardial infarction is a common disease rarely seen as a complication of bone marrow transplantation in young patients. We report on a 25-year-old patient 3.5 years after bone marrow transplantation who suffered an acute anterior wall myocardial infarction complicated by cardiogenic shock. The patient was treated with thrombolysis and emergent coronary angioplasty but died a few hours following admission. We suggest that the combination of low-dose chest irradiation and prolonged immunosuppression with graft-versus-host disease contributed to the development of the coronary artery disease in this patient. Though rarely encountered, physicians caring for young patients after bone marrow transplantation should be aware of potential ischemic complications.

AB - Acute myocardial infarction is a common disease rarely seen as a complication of bone marrow transplantation in young patients. We report on a 25-year-old patient 3.5 years after bone marrow transplantation who suffered an acute anterior wall myocardial infarction complicated by cardiogenic shock. The patient was treated with thrombolysis and emergent coronary angioplasty but died a few hours following admission. We suggest that the combination of low-dose chest irradiation and prolonged immunosuppression with graft-versus-host disease contributed to the development of the coronary artery disease in this patient. Though rarely encountered, physicians caring for young patients after bone marrow transplantation should be aware of potential ischemic complications.

KW - Bone marrow transplantation

KW - Graft-versus-host disease

KW - Myocardial infarction

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ER -

Acute myocardial infarction after bone marrow transplantation: An unsuspected late complication

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Keywords

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