Adenylate cyclase responses to sucrose stimulation in membranes of pig circumvallate taste papillae

Michael Naim*, Tal Ronen, Benjamin J. Striem, Martha Levinson, Uri Zehavi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

47 Scopus citations

Abstract

1. 1. Typical adenylate cyclase (AC) responses to guanine nucleotides were found in membranes of pig circumvallate (CV) taste papillae. 2. 2. Sucrose stimulated AC activity in the CV membranes and this stimulation was GTP dependent and tissue specific. 3. 3. The stimulatory effect of sucrose in the CV membranes was dependent on the concentration of membranes used in the AC assay. 4. 4. This study provides the first biochemical data on cellular transduction of taste in the pig, compares positively to preliminary results in cattle and supports recent suggetions for a role of cAMP in sweet taste transduction.

Original languageEnglish
Pages (from-to)455-458
Number of pages4
JournalComparative Biochemistry and Physiology Part - B: Biochemistry and Molecular Biology
Volume100
Issue number3
DOIs
StatePublished - 1991

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