TY - JOUR
T1 - Adenylate cyclase responses to sucrose stimulation in membranes of pig circumvallate taste papillae
AU - Naim, Michael
AU - Ronen, Tal
AU - Striem, Benjamin J.
AU - Levinson, Martha
AU - Zehavi, Uri
PY - 1991
Y1 - 1991
N2 - 1. 1. Typical adenylate cyclase (AC) responses to guanine nucleotides were found in membranes of pig circumvallate (CV) taste papillae. 2. 2. Sucrose stimulated AC activity in the CV membranes and this stimulation was GTP dependent and tissue specific. 3. 3. The stimulatory effect of sucrose in the CV membranes was dependent on the concentration of membranes used in the AC assay. 4. 4. This study provides the first biochemical data on cellular transduction of taste in the pig, compares positively to preliminary results in cattle and supports recent suggetions for a role of cAMP in sweet taste transduction.
AB - 1. 1. Typical adenylate cyclase (AC) responses to guanine nucleotides were found in membranes of pig circumvallate (CV) taste papillae. 2. 2. Sucrose stimulated AC activity in the CV membranes and this stimulation was GTP dependent and tissue specific. 3. 3. The stimulatory effect of sucrose in the CV membranes was dependent on the concentration of membranes used in the AC assay. 4. 4. This study provides the first biochemical data on cellular transduction of taste in the pig, compares positively to preliminary results in cattle and supports recent suggetions for a role of cAMP in sweet taste transduction.
UR - http://www.scopus.com/inward/record.url?scp=0025719932&partnerID=8YFLogxK
U2 - 10.1016/0305-0491(91)90203-P
DO - 10.1016/0305-0491(91)90203-P
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C2 - 1814673
AN - SCOPUS:0025719932
SN - 0305-0491
VL - 100
SP - 455
EP - 458
JO - Comparative Biochemistry and Physiology Part - B: Biochemistry and Molecular Biology
JF - Comparative Biochemistry and Physiology Part - B: Biochemistry and Molecular Biology
IS - 3
ER -