Advanced strategies for development of vaccines against human bacterial pathogens

Abhinay Sharma; Pooja Sanduja; Aparna Anand; Pooja Mahajan; Carlos A. Guzman; Puja Yadav; Amit Awasthi; Emanuel Hanski; Meenakshi Dua; Atul Kumar Johri

doi:10.1007/s11274-021-03021-6

Advanced strategies for development of vaccines against human bacterial pathogens

Abhinay Sharma
, Pooja Sanduja
, Aparna Anand
, Pooja Mahajan
, Carlos A. Guzman
, Puja Yadav
, Amit Awasthi
, Emanuel Hanski
, Meenakshi Dua
, Atul Kumar Johri^*

^*Corresponding author for this work

Institute for Medical Research Israel-Canada (IMRIC)

Research output: Contribution to journal › Review article › peer-review

7 Scopus citations

Abstract

Infectious diseases are one of the main grounds of death and disabilities in human beings globally. Lack of effective treatment and immunization for many deadly infectious diseases and emerging drug resistance in pathogens underlines the need to either develop new vaccines or sufficiently improve the effectiveness of currently available drugs and vaccines. In this review, we discuss the application of advanced tools like bioinformatics, genomics, proteomics and associated techniques for a rational vaccine design.

Original language	English
Article number	67
Journal	World Journal of Microbiology and Biotechnology
Volume	37
Issue number	4
DOIs	https://doi.org/10.1007/s11274-021-03021-6
State	Published - Apr 2021

Bibliographical note

Publisher Copyright:
© 2021, The Author(s).

Keywords

Genomics
Human pathogens
Protein microarray
Proteomics
Reverse vaccinology
Vaccine

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10.1007/s11274-021-03021-6

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title = "Advanced strategies for development of vaccines against human bacterial pathogens",

abstract = "Infectious diseases are one of the main grounds of death and disabilities in human beings globally. Lack of effective treatment and immunization for many deadly infectious diseases and emerging drug resistance in pathogens underlines the need to either develop new vaccines or sufficiently improve the effectiveness of currently available drugs and vaccines. In this review, we discuss the application of advanced tools like bioinformatics, genomics, proteomics and associated techniques for a rational vaccine design.",

keywords = "Genomics, Human pathogens, Protein microarray, Proteomics, Reverse vaccinology, Vaccine",

author = "Abhinay Sharma and Pooja Sanduja and Aparna Anand and Pooja Mahajan and Guzman, \{Carlos A.\} and Puja Yadav and Amit Awasthi and Emanuel Hanski and Meenakshi Dua and Johri, \{Atul Kumar\}",

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doi = "10.1007/s11274-021-03021-6",

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AU - Sharma, Abhinay

AU - Sanduja, Pooja

AU - Anand, Aparna

AU - Mahajan, Pooja

AU - Guzman, Carlos A.

AU - Yadav, Puja

AU - Awasthi, Amit

AU - Hanski, Emanuel

AU - Dua, Meenakshi

AU - Johri, Atul Kumar

PY - 2021/4

Y1 - 2021/4

N2 - Infectious diseases are one of the main grounds of death and disabilities in human beings globally. Lack of effective treatment and immunization for many deadly infectious diseases and emerging drug resistance in pathogens underlines the need to either develop new vaccines or sufficiently improve the effectiveness of currently available drugs and vaccines. In this review, we discuss the application of advanced tools like bioinformatics, genomics, proteomics and associated techniques for a rational vaccine design.

AB - Infectious diseases are one of the main grounds of death and disabilities in human beings globally. Lack of effective treatment and immunization for many deadly infectious diseases and emerging drug resistance in pathogens underlines the need to either develop new vaccines or sufficiently improve the effectiveness of currently available drugs and vaccines. In this review, we discuss the application of advanced tools like bioinformatics, genomics, proteomics and associated techniques for a rational vaccine design.

KW - Genomics

KW - Human pathogens

KW - Protein microarray

KW - Proteomics

KW - Reverse vaccinology

KW - Vaccine

UR - https://www.scopus.com/pages/publications/85102936813

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JO - World Journal of Microbiology and Biotechnology

JF - World Journal of Microbiology and Biotechnology

IS - 4

M1 - 67

ER -

Advanced strategies for development of vaccines against human bacterial pathogens

Abstract

Bibliographical note

Keywords

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