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Aging disrupts circadian gene regulation and function in macrophages
Eran Blacher
, Connie Tsai
, Lev Litichevskiy
, Zohar Shipony
, Chinyere Agbaegbu Iweka
, Kai Markus Schneider
, Bayarsaikhan Chuluun
, H. Craig Heller
, Vilas Menon
, Christoph A. Thaiss
*
, Katrin I. Andreasson
*
*
Corresponding author for this work
Research output
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Article
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peer-review
118
Scopus citations
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Keyphrases
Aging
100%
Macrophages
100%
Clock Genes
100%
Gene Regulation
100%
Gene Function
100%
KLF4
66%
Innate Immune Response
33%
Gene Transcription
33%
Transcription Factor
16%
Neurodegeneration
16%
Inflammatory Diseases
16%
Genetic Variants
16%
Immune Response
16%
Ablation
16%
Phagocytic Activity
16%
Bone Marrow
16%
Bacterial Infection
16%
Lipopolysaccharide
16%
Phagocytosis
16%
Frailty
16%
Cell Differentiation
16%
Age-associated
16%
Increased Vulnerability
16%
Aging Effect
16%
Cell Reprogramming
16%
Chromatin Accessibility
16%
Tissue-resident Macrophages
16%
Immune Homeostasis
16%
Diurnal Rhythm
16%
Aging Susceptibility
16%
Protective Immune Response
16%
Macrophage Phagocytosis
16%
Blood Response
16%
Monocyte Trafficking
16%
Diurnal Expression
16%
Immunology and Microbiology
Macrophage
100%
Gene Control
100%
Gene Function
100%
Kruppel Like Factor 4
50%
Phagocytosis
37%
Immune Response
25%
Genetic Transcription
25%
Infection
25%
Transcription Factors
12%
Homeostasis
12%
Inflammatory Disorder
12%
Circadian Rhythm
12%
Atherosclerosis
12%
Cell Differentiation
12%
Innate Immune System
12%
Nuclear Reprogramming
12%
Susceptibility
12%
Neuroscience
Gene Control
100%
Macrophage
100%
Gene Function
100%
KLF4
50%
Phagocytosis
37%
Genetic Transcription
25%
Transcription Factors
12%
Neurodegeneration
12%
Cellular Differentiation
12%
Lipopolysaccharide
12%
Nuclear Reprogramming
12%
Circadian Rhythm
12%