AMP-activated protein kinase (AMPK) mediates nutrient regulation of thioredoxin-interacting protein (TXNIP) in pancreatic beta-cells

Keyphrases

• Acid Effect 5%
• AMP-activated Protein Kinase 100%
• Apoptosis 5%
• B Cells 5%
• Beta Cell Line 5%
• Biological Processes 5%
• Cellular Energy 5%
• ChREBP 16%
• Diabetes 5%
• Diabetes Management 5%
• Divergent Effects 5%
• Energy Control 5%
• Energy Sensing 5%
• Esterification 5%
• Fatty Acid β-oxidation 5%
• Fatty Acids 27%
• Glucolipotoxicity 5%
• Glucose Effect 11%
• High Glucose 5%
• Hyperglycemia 5%
• Inflammation 5%
• Islet 5%
• Knockdown 5%
• Metabolic Homeostasis 5%
• Nuclear Entry 5%
• Nutrient Regulation 100%
• Oleate 5%
• Opposing Effects 11%
• Palmitate 33%
• Pancreatic β-cells 100%
• Pathophysiology of Diabetes 5%
• Pharmacologic 5%
• Protective Response 5%
• Protein Activity 5%
• Protein Expression 22%
• Protein Kinase Activity 11%
• Saturated Long-chain Fatty Acids 5%
• Thioredoxin-interacting Protein (TXNIP) 100%
• β-cell Apoptosis 11%

Biochemistry, Genetics and Molecular Biology

• AMP-activated Protein Kinase 100%
• Beta Oxidation 6%
• Binding Protein 20%
• Biological Phenomena and Functions Concerning the Entire Organism 6%
• Cell Energy 6%
• Esterification 6%
• Homeostasis 6%
• Hyperglycemia 6%
• Mediator 6%
• Palmitic Acid 40%
• Promoter Region 6%
• Protein Expression 26%
• Response Element 20%
• Thioredoxin 100%
• Transcription 13%