Amplified electrochemical detection of DNA through the aggregation of Au nanoparticles on electrodes and the incorporation of methylene blue into the DNA-crosslinked structure

Di Li, Yiming Yan, Agnieszka Wieckowska, Itamar Willner*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

103 Scopus citations

Abstract

The amplified electrochemical sensing of DNA is accomplished by the analyte-induced aggregation of nucleic acid-functionalized Au nanoparticles, deposition of the aggregates on a thiolated monolayer-functionalized electrode, and the voltammetric analysis of the redox-active methylene blue intercalated in the nucleic acid duplexes associated with the aggregates.

Original languageEnglish
Pages (from-to)3544-3546
Number of pages3
JournalChemical Communications
Issue number34
DOIs
StatePublished - 2007

Fingerprint

Dive into the research topics of 'Amplified electrochemical detection of DNA through the aggregation of Au nanoparticles on electrodes and the incorporation of methylene blue into the DNA-crosslinked structure'. Together they form a unique fingerprint.

Cite this