Amylopectinosis of the fatal epilepsy Lafora disease resists autophagic glycogen catabolism

Jun Wu; Or Kakhlon; Miguel Weil; Alexander Lossos; Berge A. Minassian

doi:10.1038/s44321-024-00063-9

Amylopectinosis of the fatal epilepsy Lafora disease resists autophagic glycogen catabolism

Jun Wu
, Or Kakhlon
, Miguel Weil
, Alexander Lossos
, Berge A. Minassian^*

^*Corresponding author for this work

Institute for Medical Research Israel-Canada (IMRIC)

Research output: Contribution to journal › Letter › peer-review

3 Scopus citations

Abstract

In this Correspondence, B. Minassian and colleagues report that GHF201, an autophagy activator shown to diminish abnormal glycogen aggregates in a mouse model of Adult Polyglucosan Body Disease, fails to reduce such accumulations in a mouse model of Lafora disease. (Figure presented.)

Original language	English
Pages (from-to)	1047-1050
Number of pages	4
Journal	EMBO Molecular Medicine
Volume	16
Issue number	5
DOIs	https://doi.org/10.1038/s44321-024-00063-9
State	Published - 16 May 2024

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abstract = "In this Correspondence, B. Minassian and colleagues report that GHF201, an autophagy activator shown to diminish abnormal glycogen aggregates in a mouse model of Adult Polyglucosan Body Disease, fails to reduce such accumulations in a mouse model of Lafora disease. (Figure presented.)",

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AU - Minassian, Berge A.

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Amylopectinosis of the fatal epilepsy Lafora disease resists autophagic glycogen catabolism

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