TY - JOUR
T1 - An alternative method for calculating simple pharmacokinetic parameters for zero‐order absorption and first‐order elimination processes
AU - Bialer, Meir
PY - 1981
Y1 - 1981
N2 - An alternative way to the classical method is presented for calculating the relevant pharmacokinetic parameters for zero‐order absorption and first‐order elimination processes. Although the equations were derived using the one compartment body model, some of them are applicable to the multicomponent body model as well. The method presented is useful whether or not a steady state is reached.
AB - An alternative way to the classical method is presented for calculating the relevant pharmacokinetic parameters for zero‐order absorption and first‐order elimination processes. Although the equations were derived using the one compartment body model, some of them are applicable to the multicomponent body model as well. The method presented is useful whether or not a steady state is reached.
KW - body model
KW - First‐order elimination
KW - Half‐life
KW - Infusion duration time
KW - lime
KW - One compartment
KW - Steady state
KW - Zero‐order absorption
UR - http://www.scopus.com/inward/record.url?scp=0019824339&partnerID=8YFLogxK
U2 - 10.1002/bdd.2510020404
DO - 10.1002/bdd.2510020404
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
C2 - 7317571
AN - SCOPUS:0019824339
SN - 0142-2782
VL - 2
SP - 323
EP - 327
JO - Biopharmaceutics and Drug Disposition
JF - Biopharmaceutics and Drug Disposition
IS - 4
ER -