An alternative method for calculating simple pharmacokinetic parameters for zero‐order absorption and first‐order elimination processes

Meir Bialer*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

An alternative way to the classical method is presented for calculating the relevant pharmacokinetic parameters for zero‐order absorption and first‐order elimination processes. Although the equations were derived using the one compartment body model, some of them are applicable to the multicomponent body model as well. The method presented is useful whether or not a steady state is reached.

Original languageEnglish
Pages (from-to)323-327
Number of pages5
JournalBiopharmaceutics and Drug Disposition
Volume2
Issue number4
DOIs
StatePublished - 1981

Keywords

  • body model
  • First‐order elimination
  • Half‐life
  • Infusion duration time
  • lime
  • One compartment
  • Steady state
  • Zero‐order absorption

Fingerprint

Dive into the research topics of 'An alternative method for calculating simple pharmacokinetic parameters for zero‐order absorption and first‐order elimination processes'. Together they form a unique fingerprint.

Cite this