An Au nanoparticle/bisbipyridinium cyclophane-functionalized ion- sensitive field-effect transistor for the sensing of adrenaline

Andrei B. Kharitonov; Andrew N. Shipway; Itamar Willner

doi:10.1021/ac990997s

An Au nanoparticle/bisbipyridinium cyclophane-functionalized ion- sensitive field-effect transistor for the sensing of adrenaline

Andrei B. Kharitonov
, Andrew N. Shipway
, Itamar Willner^*

^*Corresponding author for this work

Institute of Chemistry

Research output: Contribution to journal › Article › peer-review

77 Scopus citations

Abstract

A film consisting of polyethyleneimine (PEI), Au nanoparticles (12 ± 1 nm) and coadsorbed cyclobis(paraquat-p-phenylene) (1) was assembled as a sensing interface on the Al₂₃ insulating layer of an ion-sensitive field- effect transistor (ISFET). Adrenaline (2) was sensed by the functionalized ISFET with a detection limit of 1 x 10^-6 M. The sensing ability of the nanostructured device for the analysis of adrenaline originates from the preconcentration of the analyte in the cyclophane by π-π donor-acceptor interactions. Analysis of adrenaline is accomplished by the measurement of the source-drain current, I(sd), or by the gate-source voltage, V(gs). The sensing device is reusable (at least 100 cycles) and exhibits high stability.

Original language	English
Pages (from-to)	5441-5443
Number of pages	3
Journal	Analytical Chemistry
Volume	71
Issue number	23
DOIs	https://doi.org/10.1021/ac990997s
State	Published - 1 Dec 1999

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title = "An Au nanoparticle/bisbipyridinium cyclophane-functionalized ion- sensitive field-effect transistor for the sensing of adrenaline",

abstract = "A film consisting of polyethyleneimine (PEI), Au nanoparticles (12 ± 1 nm) and coadsorbed cyclobis(paraquat-p-phenylene) (1) was assembled as a sensing interface on the Al23 insulating layer of an ion-sensitive field- effect transistor (ISFET). Adrenaline (2) was sensed by the functionalized ISFET with a detection limit of 1 x 10-6 M. The sensing ability of the nanostructured device for the analysis of adrenaline originates from the preconcentration of the analyte in the cyclophane by π-π donor-acceptor interactions. Analysis of adrenaline is accomplished by the measurement of the source-drain current, I(sd), or by the gate-source voltage, V(gs). The sensing device is reusable (at least 100 cycles) and exhibits high stability.",

author = "Kharitonov, \{Andrei B.\} and Shipway, \{Andrew N.\} and Itamar Willner",

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T1 - An Au nanoparticle/bisbipyridinium cyclophane-functionalized ion- sensitive field-effect transistor for the sensing of adrenaline

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AU - Shipway, Andrew N.

AU - Willner, Itamar

PY - 1999/12/1

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N2 - A film consisting of polyethyleneimine (PEI), Au nanoparticles (12 ± 1 nm) and coadsorbed cyclobis(paraquat-p-phenylene) (1) was assembled as a sensing interface on the Al23 insulating layer of an ion-sensitive field- effect transistor (ISFET). Adrenaline (2) was sensed by the functionalized ISFET with a detection limit of 1 x 10-6 M. The sensing ability of the nanostructured device for the analysis of adrenaline originates from the preconcentration of the analyte in the cyclophane by π-π donor-acceptor interactions. Analysis of adrenaline is accomplished by the measurement of the source-drain current, I(sd), or by the gate-source voltage, V(gs). The sensing device is reusable (at least 100 cycles) and exhibits high stability.

AB - A film consisting of polyethyleneimine (PEI), Au nanoparticles (12 ± 1 nm) and coadsorbed cyclobis(paraquat-p-phenylene) (1) was assembled as a sensing interface on the Al23 insulating layer of an ion-sensitive field- effect transistor (ISFET). Adrenaline (2) was sensed by the functionalized ISFET with a detection limit of 1 x 10-6 M. The sensing ability of the nanostructured device for the analysis of adrenaline originates from the preconcentration of the analyte in the cyclophane by π-π donor-acceptor interactions. Analysis of adrenaline is accomplished by the measurement of the source-drain current, I(sd), or by the gate-source voltage, V(gs). The sensing device is reusable (at least 100 cycles) and exhibits high stability.

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An Au nanoparticle/bisbipyridinium cyclophane-functionalized ion- sensitive field-effect transistor for the sensing of adrenaline

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