An evaluation of pharmacist knowledge on treatment with antiepileptic drugs

Yifat Roth, Miri Y. Neufeld, Ilan Blatt, Shiri Guy-Alfandary, Sivan Rasaby, Dana Ekstein*, Sara Eyal

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Purpose As pharmacists play an important role in managing antiepileptic drug (AED) therapy, they should be aware of different aspects of the treatment. Our aim was to evaluate pharmacists' knowledge of the pharmacological treatment of epilepsy, and their recommendations under hypothetical situations, through a written questionnaire. Methods The questionnaire included 22 questions divided into three sections: demographic data (eight questions), knowledge of specific aspects of AED therapy (true/false; four questions), and actions taken in theoretical situations involving AED therapy (multiple choice; ten questions). The questionnaire was distributed to pharmacists practicing in Israel and working in pharmacies and/or participating in professional meetings and continued education programs. Results One hundred and twenty one pharmacists completed the questionnaire (response rate 19%). The mean overall score was 48 ± 15% correct answers. Most pharmacists were aware of the need to continue AED treatment during pregnancy, the risk of generic switches, and the need to call the physician for loss of seizure control (92%, 89% and 81% of responders, respectively). Twelve percent identified correctly all three situations in which the clinicians should be contacted urgently, and 27% did not identify any of them. The total score was related to the academic degree (PharmD vs. other) and to the duration since training completion. Conclusion Pharmacists were knowledgeable regarding some aspects of care of people with epilepsy. However, our study, as in previous studies among health care professionals, identified some gaps in knowledge. These findings indicate the need for better education of pharmacists regarding epilepsy and its treatment.

Original languageAmerican English
Pages (from-to)60-65
Number of pages6
JournalSeizure : the journal of the British Epilepsy Association
StatePublished - 1 Jan 2016

Bibliographical note

Funding Information:
We thank Adv. Ariel Averbuch from PSI, Mr. Shay Shabat from Super-Pharm, Dr. Yossef Lomnicky, Dr. Noya Machtiger, Ms. Sara Gavish and Ms. Inbal Sweet from Maccabi HMO, and Prof. Amnon Hoffman from the Hebrew University's School of Pharmacy for their assistance in project approval. We thank Zvi Roth for his help in questionnaire distribution and language correction. We also thank the pharmacist respondents for their time and input. This work is part of the PharmD thesis of Ms. Yifat Roth. Appendix A

Publisher Copyright:
© 2015 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.


  • Antiepileptic drugs
  • Interactions
  • Knowledge
  • Pharmacists
  • Questionnaires
  • Women's health


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