An Improved Procedure for the Isolation of Medicagenic Acid 3-O-β-D-Glucopyranoside from Alfalfa Roots and Its Antifungal Activity on Plant Pathogens

Mordekhai Levy, Uri Zehavi, Michael Naim, Itzhack Polacheck

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

2β-Hydroxy-3β-O-(β-D-glucopyranosyl)-Δ12-oleanene-23,28-dioic acid, known also as medicagenic acid 3-O-β-D-glucopyranoside, was isolated from alfalfa roots in pure form and was shown to possess potent fungistatic effects against Trichoderma viride, Sclerotium rolfsii, Rhizopus mucco, Aspergillus niger, Phytophthora cinamommi, and Fusarium oxysporum f. sp. lycopersici: i.e., mycelial growth inhibition of 95%, 86%, 68%, 53%, 51%, and 52%, respectively, for concentrations of 40 μg/mL and ID50 of 1.4, 2.3, 4.1, 1.7, 40, and 10.5 μg/mL, respectively.

Original languageEnglish
Pages (from-to)960-963
Number of pages4
JournalJournal of Agricultural and Food Chemistry
Volume34
Issue number6
DOIs
StatePublished - 1986

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