TY - JOUR
T1 - An infant with a diagnostically challenging hepatic teratoma, hypofibrinogenemia, and adrenal neuroblastoma
T2 - Case report
AU - Fried, Iris
AU - Rom-Gross, Eitan
AU - Finegold, Milton
AU - Simanovsky, Natalia
AU - Revel-Vilk, Shoshana
AU - Ben-Neriah, Ziva
AU - Weintraub, Michael
AU - Pappo, Orit
AU - Meir, Karen
N1 - Publisher Copyright:
© 2015 Society for Pediatric Pathology.
PY - 2015/5/1
Y1 - 2015/5/1
N2 - Teratomas of the liver are exceedingly rare. Neuroblastoma is the most common, extracranial solid tumor of infancy. We describe the case of a 2-month-old, female infant who presented with an abdominal mass arising in the right lobe of the liver, and a severe coagulopathy, which necessitated cryoprecipitate infusion. Biopsy was interpreted as hepatoblastoma. Following resection, difficulty classifying the mass led to several consultations, and an eventual diagnosis of teratoma. During follow-up, the patient was diagnosed with right adrenal neuroblastoma, which, in retrospect, had been present before the hepatic resection. To our knowledge, these 2 tumors have never been reported together, or in combination with isolated hypofibrinogenemia.
AB - Teratomas of the liver are exceedingly rare. Neuroblastoma is the most common, extracranial solid tumor of infancy. We describe the case of a 2-month-old, female infant who presented with an abdominal mass arising in the right lobe of the liver, and a severe coagulopathy, which necessitated cryoprecipitate infusion. Biopsy was interpreted as hepatoblastoma. Following resection, difficulty classifying the mass led to several consultations, and an eventual diagnosis of teratoma. During follow-up, the patient was diagnosed with right adrenal neuroblastoma, which, in retrospect, had been present before the hepatic resection. To our knowledge, these 2 tumors have never been reported together, or in combination with isolated hypofibrinogenemia.
KW - Hepatoblastoma
KW - Hypofibrinogenemia
KW - Liver tumor
KW - Neuroblastoma
KW - Teratoma
UR - http://www.scopus.com/inward/record.url?scp=84929669954&partnerID=8YFLogxK
U2 - 10.2350/13-08-1361-CR.1
DO - 10.2350/13-08-1361-CR.1
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C2 - 25756389
AN - SCOPUS:84929669954
SN - 1093-5266
VL - 18
SP - 251
EP - 256
JO - Pediatric and Developmental Pathology
JF - Pediatric and Developmental Pathology
IS - 3
ER -
