An integrated computational pipeline and database to support whole-genome sequence annotation.

C. J. Mungall; S. Misra; B. P. Berman; J. Carlson; E. Frise; N. Harris; B. Marshall; S. Shu; J. S. Kaminker; S. E. Prochnik; C. D. Smith; E. Smith; J. L. Tupy; C. Wiel; G. M. Rubin; S. E. Lewis

An integrated computational pipeline and database to support whole-genome sequence annotation.

C. J. Mungall^*, S. Misra, B. P. Berman, J. Carlson, E. Frise, N. Harris, B. Marshall, S. Shu, J. S. Kaminker, S. E. Prochnik, C. D. Smith, E. Smith, J. L. Tupy, C. Wiel, G. M. Rubin, S. E. Lewis

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

31 Scopus citations

Abstract

We describe here our experience in annotating the Drosophila melanogaster genome sequence, in the course of which we developed several new open-source software tools and a database schema to support large-scale genome annotation. We have developed these into an integrated and reusable software system for whole-genome annotation. The key contributions to overall annotation quality are the marshalling of high-quality sequences for alignments and the design of a system with an adaptable and expandable flexible architecture.

Original language	American English
Pages (from-to)	RESEARCH0081
Journal	Genome Biology
Volume	3
Issue number	12
State	Published - 2002
Externally published	Yes

Cite this

@article{9c3c8d9664a14dcb86f6829f8bd80820,

title = "An integrated computational pipeline and database to support whole-genome sequence annotation.",

abstract = "We describe here our experience in annotating the Drosophila melanogaster genome sequence, in the course of which we developed several new open-source software tools and a database schema to support large-scale genome annotation. We have developed these into an integrated and reusable software system for whole-genome annotation. The key contributions to overall annotation quality are the marshalling of high-quality sequences for alignments and the design of a system with an adaptable and expandable flexible architecture.",

author = "Mungall, {C. J.} and S. Misra and Berman, {B. P.} and J. Carlson and E. Frise and N. Harris and B. Marshall and S. Shu and Kaminker, {J. S.} and Prochnik, {S. E.} and Smith, {C. D.} and E. Smith and Tupy, {J. L.} and C. Wiel and Rubin, {G. M.} and Lewis, {S. E.}",

year = "2002",

language = "American English",

volume = "3",

pages = "RESEARCH0081",

journal = "Genome Biology",

issn = "1474-7596",

publisher = "BioMed Central Ltd.",

number = "12",

}

TY - JOUR

T1 - An integrated computational pipeline and database to support whole-genome sequence annotation.

AU - Mungall, C. J.

AU - Misra, S.

AU - Berman, B. P.

AU - Carlson, J.

AU - Frise, E.

AU - Harris, N.

AU - Marshall, B.

AU - Shu, S.

AU - Kaminker, J. S.

AU - Prochnik, S. E.

AU - Smith, C. D.

AU - Smith, E.

AU - Tupy, J. L.

AU - Wiel, C.

AU - Rubin, G. M.

AU - Lewis, S. E.

PY - 2002

Y1 - 2002

N2 - We describe here our experience in annotating the Drosophila melanogaster genome sequence, in the course of which we developed several new open-source software tools and a database schema to support large-scale genome annotation. We have developed these into an integrated and reusable software system for whole-genome annotation. The key contributions to overall annotation quality are the marshalling of high-quality sequences for alignments and the design of a system with an adaptable and expandable flexible architecture.

AB - We describe here our experience in annotating the Drosophila melanogaster genome sequence, in the course of which we developed several new open-source software tools and a database schema to support large-scale genome annotation. We have developed these into an integrated and reusable software system for whole-genome annotation. The key contributions to overall annotation quality are the marshalling of high-quality sequences for alignments and the design of a system with an adaptable and expandable flexible architecture.

UR - http://www.scopus.com/inward/record.url?scp=0012302769&partnerID=8YFLogxK

M3 - Review article

C2 - 12537570

AN - SCOPUS:0012302769

SN - 1474-7596

VL - 3

SP - RESEARCH0081

JO - Genome Biology

JF - Genome Biology

IS - 12

ER -

An integrated computational pipeline and database to support whole-genome sequence annotation.

Abstract

Other files and links

Fingerprint

Cite this