An integrated view of the regulation of NKG2D ligands

Noam Stern-Ginossar, Ofer Mandelboim*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

70 Scopus citations

Abstract

NKG2D is one of the best characterized activating receptors and is expressed on natural killer cells and on various T-cell subsets. This receptor recognizes several different ligands that are induced by cellular stresses. In this review, we described the mechanisms controlling the expression of NKG2D ligands, with the emphasis on post-transcriptional and post-translational regulation.

Original languageAmerican English
Pages (from-to)1-6
Number of pages6
JournalImmunology
Volume128
Issue number1
DOIs
StatePublished - Sep 2009

Keywords

  • Innate immunity
  • MicroRNAs
  • NKG2D
  • Natural killer cells
  • Stress

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