Analysis of fatty acid anhydrides and polyanhydrides

Neeraj Kumar, Mahesh Krishnan, Tony Azzam, Amir Magora, Majeti N.V. Ravikumar, Douglas R. Flanagan, Abraham J. Domb*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

Acid anhydrides are considered as important reagents in organic and peptide synthesis and in recent years for the formation of prodrugs and biomaterials for controlled release of drugs. This article highlights the analysis of mixed anhydrides and polyanhydrides synthesized by various methods. Analytical methods including HPLC, GLC, 1H NMR and IR spectroscopy are described for the determination of anhydride hydrolysis and amidation.

Original languageEnglish
Pages (from-to)257-272
Number of pages16
JournalAnalytica Chimica Acta
Volume465
Issue number1-2
DOIs
StatePublished - 16 Aug 2002

Keywords

  • Anhydride
  • Anhydride analysis
  • Hydrolytic degradation
  • Mixed anhydride
  • Prodrug

Fingerprint

Dive into the research topics of 'Analysis of fatty acid anhydrides and polyanhydrides'. Together they form a unique fingerprint.

Cite this