Angiogenic potential of mesenchymal stem cells derived from patients with diabetes seeded on decellularized micro fragments

Assaf Assis; Yechiel N. Gellman; Avivit Cahn; Amir Haze; Sandra Camargo; Eduardo Mitrani

doi:10.1016/j.jdiacomp.2021.108001

Angiogenic potential of mesenchymal stem cells derived from patients with diabetes seeded on decellularized micro fragments

Assaf Assis, Yechiel N. Gellman, Avivit Cahn, Amir Haze, Sandra Camargo, Eduardo Mitrani^*

^*Corresponding author for this work

Alexander Silberman Institute of Life Sciences

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Mesenchymal stem cells (MSCs) are a potential source of angiogenic factors which may promote wound healing in poorly vascularized diabetic foot ulcers. We demonstrate that MSCs of patients with diabetic foot ulcers seeded on decellularized micro-fragments transcribe and secrete angiogenic factors in amounts comparable to MSCs derived from healthy individuals.

Original language	English
Article number	108001
Journal	Journal of Diabetes and its Complications
Volume	35
Issue number	10
DOIs	https://doi.org/10.1016/j.jdiacomp.2021.108001
State	Published - Oct 2021

Bibliographical note

Publisher Copyright:
© 2021 Elsevier Inc.

Keywords

Angiogenesis
Angiogenic factors
Diabetes
Mesenchymal stem cells
Tissue engineering

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jdiacomp.2021.108001

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abstract = "Mesenchymal stem cells (MSCs) are a potential source of angiogenic factors which may promote wound healing in poorly vascularized diabetic foot ulcers. We demonstrate that MSCs of patients with diabetic foot ulcers seeded on decellularized micro-fragments transcribe and secrete angiogenic factors in amounts comparable to MSCs derived from healthy individuals.",

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author = "Assaf Assis and Gellman, {Yechiel N.} and Avivit Cahn and Amir Haze and Sandra Camargo and Eduardo Mitrani",

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AU - Assis, Assaf

AU - Gellman, Yechiel N.

AU - Cahn, Avivit

AU - Haze, Amir

AU - Camargo, Sandra

AU - Mitrani, Eduardo

PY - 2021/10

Y1 - 2021/10

N2 - Mesenchymal stem cells (MSCs) are a potential source of angiogenic factors which may promote wound healing in poorly vascularized diabetic foot ulcers. We demonstrate that MSCs of patients with diabetic foot ulcers seeded on decellularized micro-fragments transcribe and secrete angiogenic factors in amounts comparable to MSCs derived from healthy individuals.

AB - Mesenchymal stem cells (MSCs) are a potential source of angiogenic factors which may promote wound healing in poorly vascularized diabetic foot ulcers. We demonstrate that MSCs of patients with diabetic foot ulcers seeded on decellularized micro-fragments transcribe and secrete angiogenic factors in amounts comparable to MSCs derived from healthy individuals.

KW - Angiogenesis

KW - Angiogenic factors

KW - Diabetes

KW - Mesenchymal stem cells

KW - Tissue engineering

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ER -

Angiogenic potential of mesenchymal stem cells derived from patients with diabetes seeded on decellularized micro fragments

Abstract

Bibliographical note

Keywords

UN SDGs

Access to Document

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