Angiotensin increases microsomal (Na+-K+-ATPase activity in several tissues

Y. Gutman*, Y. Shamir, D. Glushevitzky, S. Hochman

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

Angiotensin increased microsomal (Na+K+)-activated ATPase from rat hypothalamus, mucosa of colon and bovine adrenal cortex but not brain cortex. Angiotensin did not change significantly Mg2+-ATPase in these tissues. Enhancement by angiotensin was evident at concentrations of 10-8 - 10-12 M. In bovine adrenal cortex angiotensin increased ATPase activity in the outer and not in the inner layer. Angiotensin increased ATPase activity with Na+ above 20 mM and K+ above 5 mM present simultaneously, but not with either ion alone.

Original languageEnglish
Pages (from-to)401-405
Number of pages5
JournalBiochimica et Biophysica Acta - General Subjects
Volume273
Issue number2
DOIs
StatePublished - 19 Jul 1972

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