Anti-Hepatozoon canis serum antibodies and gamonts in naturally-occurring canine monocytic ehrlichiosis

Mathios E. Mylonakis, Leonidas Leontides, Liat Gonen, Charalambos Billinis, Alexander F. Koutinas*, Gad Baneth

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


The prevalence of IgG antibodies to Hepatozoon canis and the presence of gamonts in the blood and hemolymphatic tissues were studied in dogs with canine monocytic ehrlichiosis (CME) caused by Ehrlichia canis. Both pathogens are transmitted by the tick Rhipicephalus sanguineus. Forty-five out of 69 (65.2%) dogs with CME were seropositive to H. canis by an enzyme-linked immunosorbent assay (ELISA). Intra-neutrophilic gamonts of H. canis were found in 2 out of 69 dogs (2.9%) comprising 4.5% of the seropositive dogs. The present study indicated that the prevalence of antibodies to H. canis was high among dogs with CME in an area where both infections are endemic. However, previous exposure to H. canis was not found as an important contributor to clinical or clinicopathologic abnormalities found in dogs with CME.

Original languageAmerican English
Pages (from-to)229-233
Number of pages5
JournalVeterinary Parasitology
Issue number3-4
StatePublished - 15 May 2005


  • Co-infection
  • Dog
  • Ehrlichia canis
  • Hepatozoon canis


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