Application of high-performance liquid chromatography with electrochemical detection to the determination of catecholamines in microdissected regions of the rat brain

Esther Shohami; Mark Segal; David M. Jacobowitz

doi:10.1016/0165-0270(83)90040-7

Application of high-performance liquid chromatography with electrochemical detection to the determination of catecholamines in microdissected regions of the rat brain

Esther Shohami, Mark Segal, David M. Jacobowitz^*

^*Corresponding author for this work

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

High-pressure liquid chromatography (HPLC) with electrochemical detection was applied for measurement of catecholamines in microdissected tissues from discrete brain regions. Brain areas were dissected, extracted and processed for HPLC assay without further purification. The advantage of this method is its simplicity and relatively low cost and may therefore be applied to the measurement of amines in brain micropunches.

Original language	English
Pages (from-to)	275-281
Number of pages	7
Journal	Journal of Neuroscience Methods
Volume	8
Issue number	3
DOIs	https://doi.org/10.1016/0165-0270(83)90040-7
State	Published - Jul 1983

Keywords

brain
catecholamines
HPLC-EC
micropunches

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10.1016/0165-0270(83)90040-7

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abstract = "High-pressure liquid chromatography (HPLC) with electrochemical detection was applied for measurement of catecholamines in microdissected tissues from discrete brain regions. Brain areas were dissected, extracted and processed for HPLC assay without further purification. The advantage of this method is its simplicity and relatively low cost and may therefore be applied to the measurement of amines in brain micropunches.",

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Application of high-performance liquid chromatography with electrochemical detection to the determination of catecholamines in microdissected regions of the rat brain

Abstract

Keywords

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