Architecture and development of the Neurospora crassa hypha - a model cell for polarized growth

Meritxell Riquelme; Oded Yarden; Salomon Bartnicki-Garcia; Barry Bowman; Ernestina Castro-Longoria; Stephen J. Free; Andre Fleißner; Michael Freitag; Roger R. Lew; Rosa Mouriño-Pérez; Michael Plamann; Carolyn Rasmussen; Corinna Richthammer; Robert W. Roberson; Eddy Sanchez-Leon; Stephan Seiler; Michael K. Watters

doi:10.1016/j.funbio.2011.02.008

Architecture and development of the Neurospora crassa hypha - a model cell for polarized growth

Meritxell Riquelme^*, Oded Yarden, Salomon Bartnicki-Garcia, Barry Bowman, Ernestina Castro-Longoria, Stephen J. Free, Andre Fleißner, Michael Freitag, Roger R. Lew, Rosa Mouriño-Pérez, Michael Plamann, Carolyn Rasmussen, Corinna Richthammer, Robert W. Roberson, Eddy Sanchez-Leon, Stephan Seiler, Michael K. Watters

^*Corresponding author for this work

Department of Plant Pathology and Microbiology

Research output: Contribution to journal › Article › peer-review

109 Scopus citations

Abstract

Neurospora crassa has been at the forefront of biological research from the early days of biochemical genetics to current progress being made in understanding gene and genetic network function. Here, we discuss recent developments in analysis of the fundamental form of fungal growth, development and proliferation - the hypha. Understanding the establishment and maintenance of polarity, hyphal elongation, septation, branching and differentiation are at the core of current research. The advances in the identification and functional dissection of regulatory as well as structural components of the hypha provide an expanding basis for elucidation of fundamental attributes of the fungal cell. The availability and continuous development of various molecular and microscopic tools, as utilized by an active and co-supportive research community, promises to yield additional important new discoveries on the biology of fungi.

Original language	English
Pages (from-to)	446-474
Number of pages	29
Journal	Fungal Biology
Volume	115
Issue number	6
DOIs	https://doi.org/10.1016/j.funbio.2011.02.008
State	Published - Jun 2011

Bibliographical note

Funding Information:
M. Freitag received grant support from the American Cancer Society ( RSG-08-030-01-CCG ). S. Free from the National Institutes of Health ( R01 GM078589 ). M. Riquelme from Consejo Nacional de Ciencia y Tecnología CONACyT ( U-45818Q , B0C022 ). O. Yarden from the Israel Science Foundation and the German Research Foundation ( SE1054/3-2 ). R. Mouriño from CONACyT ( SEP-2003-CO2-44724 and SEP-2007-CO2-82753 ), and UC-MEXUS/CONACyT 2007-2009 . C. Rasmussen from a postdoctoral fellowship from the American Cancer Society (# PF-08-280-01 ). S. Seiler from the German Research Foundation ( SE 1054/3-2 and SE1054/4-1 ). E. Castro from CONACyT ( CB-2006-1-61524 ). R. R. Lew from the Natural Sciences and Engineering Council of Canada . A. Fleißner from the German Research Foundation ( FL 706/1-1 ). We thank the Fungal Genetics Stock Center and the Neurospora Functional Genomics Program Project grant ( NIH P01GM068087 ) for materials and strains.

Keywords

Branching
Cell wall
Hyphal growth
Septation
Spitzenkörper

Access to Document

10.1016/j.funbio.2011.02.008

Cite this

Riquelme, M., Yarden, O., Bartnicki-Garcia, S., Bowman, B., Castro-Longoria, E., Free, S. J., Fleißner, A., Freitag, M., Lew, R. R., Mouriño-Pérez, R., Plamann, M., Rasmussen, C., Richthammer, C., Roberson, R. W., Sanchez-Leon, E., Seiler, S., & Watters, M. K. (2011). Architecture and development of the Neurospora crassa hypha - a model cell for polarized growth. Fungal Biology, 115(6), 446-474. https://doi.org/10.1016/j.funbio.2011.02.008

@article{7cac8ccbab7941149c9e053cfe710df7,

title = "Architecture and development of the Neurospora crassa hypha - a model cell for polarized growth",

abstract = "Neurospora crassa has been at the forefront of biological research from the early days of biochemical genetics to current progress being made in understanding gene and genetic network function. Here, we discuss recent developments in analysis of the fundamental form of fungal growth, development and proliferation - the hypha. Understanding the establishment and maintenance of polarity, hyphal elongation, septation, branching and differentiation are at the core of current research. The advances in the identification and functional dissection of regulatory as well as structural components of the hypha provide an expanding basis for elucidation of fundamental attributes of the fungal cell. The availability and continuous development of various molecular and microscopic tools, as utilized by an active and co-supportive research community, promises to yield additional important new discoveries on the biology of fungi.",

keywords = "Branching, Cell wall, Hyphal growth, Septation, Spitzenk{\"o}rper",

author = "Meritxell Riquelme and Oded Yarden and Salomon Bartnicki-Garcia and Barry Bowman and Ernestina Castro-Longoria and Free, {Stephen J.} and Andre Flei{\ss}ner and Michael Freitag and Lew, {Roger R.} and Rosa Mouri{\~n}o-P{\'e}rez and Michael Plamann and Carolyn Rasmussen and Corinna Richthammer and Roberson, {Robert W.} and Eddy Sanchez-Leon and Stephan Seiler and Watters, {Michael K.}",

note = "Funding Information: M. Freitag received grant support from the American Cancer Society ( RSG-08-030-01-CCG ). S. Free from the National Institutes of Health ( R01 GM078589 ). M. Riquelme from Consejo Nacional de Ciencia y Tecnolog{\'i}a CONACyT ( U-45818Q , B0C022 ). O. Yarden from the Israel Science Foundation and the German Research Foundation ( SE1054/3-2 ). R. Mouri{\~n}o from CONACyT ( SEP-2003-CO2-44724 and SEP-2007-CO2-82753 ), and UC-MEXUS/CONACyT 2007-2009 . C. Rasmussen from a postdoctoral fellowship from the American Cancer Society (# PF-08-280-01 ). S. Seiler from the German Research Foundation ( SE 1054/3-2 and SE1054/4-1 ). E. Castro from CONACyT ( CB-2006-1-61524 ). R. R. Lew from the Natural Sciences and Engineering Council of Canada . A. Flei{\ss}ner from the German Research Foundation ( FL 706/1-1 ). We thank the Fungal Genetics Stock Center and the Neurospora Functional Genomics Program Project grant ( NIH P01GM068087 ) for materials and strains. ",

year = "2011",

month = jun,

doi = "10.1016/j.funbio.2011.02.008",

language = "אנגלית",

volume = "115",

pages = "446--474",

journal = "Fungal Biology",

issn = "1878-6146",

publisher = "Elsevier",

number = "6",

}

Riquelme, M, Yarden, O, Bartnicki-Garcia, S, Bowman, B, Castro-Longoria, E, Free, SJ, Fleißner, A, Freitag, M, Lew, RR, Mouriño-Pérez, R, Plamann, M, Rasmussen, C, Richthammer, C, Roberson, RW, Sanchez-Leon, E, Seiler, S & Watters, MK 2011, 'Architecture and development of the Neurospora crassa hypha - a model cell for polarized growth', Fungal Biology, vol. 115, no. 6, pp. 446-474. https://doi.org/10.1016/j.funbio.2011.02.008

TY - JOUR

T1 - Architecture and development of the Neurospora crassa hypha - a model cell for polarized growth

AU - Riquelme, Meritxell

AU - Yarden, Oded

AU - Bartnicki-Garcia, Salomon

AU - Bowman, Barry

AU - Castro-Longoria, Ernestina

AU - Free, Stephen J.

AU - Fleißner, Andre

AU - Freitag, Michael

AU - Lew, Roger R.

AU - Mouriño-Pérez, Rosa

AU - Plamann, Michael

AU - Rasmussen, Carolyn

AU - Richthammer, Corinna

AU - Roberson, Robert W.

AU - Sanchez-Leon, Eddy

AU - Seiler, Stephan

AU - Watters, Michael K.

N1 - Funding Information: M. Freitag received grant support from the American Cancer Society ( RSG-08-030-01-CCG ). S. Free from the National Institutes of Health ( R01 GM078589 ). M. Riquelme from Consejo Nacional de Ciencia y Tecnología CONACyT ( U-45818Q , B0C022 ). O. Yarden from the Israel Science Foundation and the German Research Foundation ( SE1054/3-2 ). R. Mouriño from CONACyT ( SEP-2003-CO2-44724 and SEP-2007-CO2-82753 ), and UC-MEXUS/CONACyT 2007-2009 . C. Rasmussen from a postdoctoral fellowship from the American Cancer Society (# PF-08-280-01 ). S. Seiler from the German Research Foundation ( SE 1054/3-2 and SE1054/4-1 ). E. Castro from CONACyT ( CB-2006-1-61524 ). R. R. Lew from the Natural Sciences and Engineering Council of Canada . A. Fleißner from the German Research Foundation ( FL 706/1-1 ). We thank the Fungal Genetics Stock Center and the Neurospora Functional Genomics Program Project grant ( NIH P01GM068087 ) for materials and strains.

PY - 2011/6

Y1 - 2011/6

N2 - Neurospora crassa has been at the forefront of biological research from the early days of biochemical genetics to current progress being made in understanding gene and genetic network function. Here, we discuss recent developments in analysis of the fundamental form of fungal growth, development and proliferation - the hypha. Understanding the establishment and maintenance of polarity, hyphal elongation, septation, branching and differentiation are at the core of current research. The advances in the identification and functional dissection of regulatory as well as structural components of the hypha provide an expanding basis for elucidation of fundamental attributes of the fungal cell. The availability and continuous development of various molecular and microscopic tools, as utilized by an active and co-supportive research community, promises to yield additional important new discoveries on the biology of fungi.

AB - Neurospora crassa has been at the forefront of biological research from the early days of biochemical genetics to current progress being made in understanding gene and genetic network function. Here, we discuss recent developments in analysis of the fundamental form of fungal growth, development and proliferation - the hypha. Understanding the establishment and maintenance of polarity, hyphal elongation, septation, branching and differentiation are at the core of current research. The advances in the identification and functional dissection of regulatory as well as structural components of the hypha provide an expanding basis for elucidation of fundamental attributes of the fungal cell. The availability and continuous development of various molecular and microscopic tools, as utilized by an active and co-supportive research community, promises to yield additional important new discoveries on the biology of fungi.

KW - Branching

KW - Cell wall

KW - Hyphal growth

KW - Septation

KW - Spitzenkörper

UR - http://www.scopus.com/inward/record.url?scp=79957860549&partnerID=8YFLogxK

U2 - 10.1016/j.funbio.2011.02.008

DO - 10.1016/j.funbio.2011.02.008

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

C2 - 21640311

AN - SCOPUS:79957860549

SN - 1878-6146

VL - 115

SP - 446

EP - 474

JO - Fungal Biology

JF - Fungal Biology

IS - 6

ER -

Architecture and development of the Neurospora crassa hypha - a model cell for polarized growth

Abstract

Bibliographical note

Keywords

Access to Document

Other files and links

Fingerprint

Cite this