Arnold-Chiari malformation in a captive African lion cub

Merav H. Shamir*, Igal H. Horowitz, Boris Yakobson, Ron Ofri

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Progressive ataxia, delayed growth, dementia and tremors were noted in a female African lion (Panthera leo) cub at the Tel-Aviv Ramat-Gan Zoological Center (Israel). The lioness was 3-mo-old when clinical signs were first noticed. Repeated neurological evaluations and blood tests were conducted in an attempt to establish a diagnosis. A congenital abnormality was suspected and the lioness died 6 mo later. Post mortem examination revealed an Arnold-Chiari malformation. The abnormality was classified as a Chiari type 2 malformation, based on the herniation of the cerebellar vermis and paravermis and the slight caudal displacement of the medulla, combined with lack of displacement in other parts of the brainstem.

Original languageAmerican English
Pages (from-to)661-666
Number of pages6
JournalJournal of Wildlife Diseases
Issue number3
StatePublished - Jul 1998


  • African lion
  • Arnold-Chiari malformation
  • Case history
  • Cerebellum
  • Congenital malformation
  • Medulla
  • Panthera leo


Dive into the research topics of 'Arnold-Chiari malformation in a captive African lion cub'. Together they form a unique fingerprint.

Cite this