Abstract
This is the first report of treatment of cytomegalovirus infection with artesunate, for a stem cell transplant recipient with a newly identified foscarnet-resistant and ganciclovir-resistant DNA polymerase L776M mutation. Artesunate treatment resulted in a 1.7-2.1-log reduction in viral load by treatment day 7, with a viral half-life of 0.9-1.9 days, indicating a highly effective block in viral replication.
Original language | English |
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Pages (from-to) | 1455-1457 |
Number of pages | 3 |
Journal | Clinical Infectious Diseases |
Volume | 46 |
Issue number | 9 |
DOIs | |
State | Published - 1 May 2008 |
Externally published | Yes |