Association arrays for comparing familial total cholesterol, high density lipoprotein cholesterol, and triglyceride similarity in the israeli population by country of origin

Samuel Karlin*, Dortt Carmelli, Yechiel Friedlander, Paul T. Williams, Tirza Cohen, Yechizkel Stein

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

The method of association arrays Is applied to plasma total cholesterol, triglyceride, and high density lipoprotein cholesterol concentrations measured for 2485 young men and women aged 17-18 years and living In Jerusalem, and for their parents. These triad families are divided Into five groups according to whether both parents were born In Asia, North Africa, Europe-America, or Israel, or whether they were of mixed "origins." Stronger associations are present for all lipid and lipoprotein cholesterol variables in Asian and African families relative to families of other origins, possibly reflecting the more disciplined life-style patterns In these families relative to other families. Parent and offspring values exhibit positive association for all lipid variables In all groups. Patterns of familial similarity revealed by the association arrays are discussed In relation to historic and cultural differences among groups.

Original languageEnglish
Pages (from-to)1022-1032
Number of pages11
JournalAmerican Journal of Epidemiology
Volume116
Issue number6
DOIs
StatePublished - Dec 1982
Externally publishedYes

Keywords

  • Cholesterol
  • Lipoproteins, HDL
  • Triglycerides

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