Association of dopamine receptor D5 gene polymorphism with peculiarities of voluntary attention in schizophrenic patients and their relatives

V. E. Golimbet; M. V. Alfimova; I. K. Gritsenko; T. V. Lezheiko; R. Ebstein

doi:10.1007/s10517-008-0007-8

Association of dopamine receptor D5 gene polymorphism with peculiarities of voluntary attention in schizophrenic patients and their relatives

V. E. Golimbet^*
, M. V. Alfimova
, I. K. Gritsenko
, T. V. Lezheiko
, R. Ebstein

^*Corresponding author for this work

Department of Psychology

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

We studied the relationship between DRD5 gene polymorphism presented by microsatellites with cognitive signs in 152 schizophrenic patients, 81 mentally healthy relatives, and 125 mentally healthy control individuals. An association was found between DRD5 polymorphism with efficiency of visual voluntary attention in patients (p = 0.02) and their relatives (p = 0.006). Carriers of two copies of the 148-b.p. allele were characterized by low efficiency of attention.

Original language	English
Pages (from-to)	65-67
Number of pages	3
Journal	Bulletin of Experimental Biology and Medicine
Volume	145
Issue number	1
DOIs	https://doi.org/10.1007/s10517-008-0007-8
State	Published - 2008

Keywords

Attention
Dopamine D5 receptor gene
Schizophrenia

Access to Document

10.1007/s10517-008-0007-8

Cite this

@article{32dacfcfedb44560b462bef0b805d9b9,

title = "Association of dopamine receptor D5 gene polymorphism with peculiarities of voluntary attention in schizophrenic patients and their relatives",

abstract = "We studied the relationship between DRD5 gene polymorphism presented by microsatellites with cognitive signs in 152 schizophrenic patients, 81 mentally healthy relatives, and 125 mentally healthy control individuals. An association was found between DRD5 polymorphism with efficiency of visual voluntary attention in patients (p = 0.02) and their relatives (p = 0.006). Carriers of two copies of the 148-b.p. allele were characterized by low efficiency of attention.",

keywords = "Attention, Dopamine D5 receptor gene, Schizophrenia",

author = "Golimbet, \{V. E.\} and Alfimova, \{M. V.\} and Gritsenko, \{I. K.\} and Lezheiko, \{T. V.\} and R. Ebstein",

year = "2008",

doi = "10.1007/s10517-008-0007-8",

language = "אנגלית",

volume = "145",

pages = "65--67",

journal = "Bulletin of Experimental Biology and Medicine",

issn = "0007-4888",

publisher = "Springer",

number = "1",

}

TY - JOUR

T1 - Association of dopamine receptor D5 gene polymorphism with peculiarities of voluntary attention in schizophrenic patients and their relatives

AU - Golimbet, V. E.

AU - Alfimova, M. V.

AU - Gritsenko, I. K.

AU - Lezheiko, T. V.

AU - Ebstein, R.

PY - 2008

Y1 - 2008

N2 - We studied the relationship between DRD5 gene polymorphism presented by microsatellites with cognitive signs in 152 schizophrenic patients, 81 mentally healthy relatives, and 125 mentally healthy control individuals. An association was found between DRD5 polymorphism with efficiency of visual voluntary attention in patients (p = 0.02) and their relatives (p = 0.006). Carriers of two copies of the 148-b.p. allele were characterized by low efficiency of attention.

AB - We studied the relationship between DRD5 gene polymorphism presented by microsatellites with cognitive signs in 152 schizophrenic patients, 81 mentally healthy relatives, and 125 mentally healthy control individuals. An association was found between DRD5 polymorphism with efficiency of visual voluntary attention in patients (p = 0.02) and their relatives (p = 0.006). Carriers of two copies of the 148-b.p. allele were characterized by low efficiency of attention.

KW - Attention

KW - Dopamine D5 receptor gene

KW - Schizophrenia

UR - https://www.scopus.com/pages/publications/50149092193

U2 - 10.1007/s10517-008-0007-8

DO - 10.1007/s10517-008-0007-8

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

C2 - 19024005

AN - SCOPUS:50149092193

SN - 0007-4888

VL - 145

SP - 65

EP - 67

JO - Bulletin of Experimental Biology and Medicine

JF - Bulletin of Experimental Biology and Medicine

IS - 1

ER -

Association of dopamine receptor D5 gene polymorphism with peculiarities of voluntary attention in schizophrenic patients and their relatives

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this