ATTRITION OF TRISOMIES AS A MATERNAL SCREENING DEVICE. An Explanation of the Association of Trisomy 21 with Maternal Age

Zena Stein; Wilfred Stein; Mervyn Susser

doi:10.1016/S0140-6736(86)91046-9

ATTRITION OF TRISOMIES AS A MATERNAL SCREENING DEVICE. An Explanation of the Association of Trisomy 21 with Maternal Age

Zena Stein^*
, Wilfred Stein
, Mervyn Susser

^*Corresponding author for this work

Alexander Silberman Institute of Life Sciences

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

Analysis of published data indicates that the increased rate of trisomy 21 pregnancies with advancing maternal age is due to failure of a postulated maternal screening process between fertilisation and recognition. This mechanism may also operate in other trisomies.

Original language	English
Pages (from-to)	944-947
Number of pages	4
Journal	The Lancet
Volume	327
Issue number	8487
DOIs	https://doi.org/10.1016/S0140-6736(86)91046-9
State	Published - 26 Apr 1986

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title = "ATTRITION OF TRISOMIES AS A MATERNAL SCREENING DEVICE. An Explanation of the Association of Trisomy 21 with Maternal Age",

abstract = "Analysis of published data indicates that the increased rate of trisomy 21 pregnancies with advancing maternal age is due to failure of a postulated maternal screening process between fertilisation and recognition. This mechanism may also operate in other trisomies.",

author = "Zena Stein and Wilfred Stein and Mervyn Susser",

year = "1986",

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AU - Stein, Wilfred

AU - Susser, Mervyn

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Y1 - 1986/4/26

N2 - Analysis of published data indicates that the increased rate of trisomy 21 pregnancies with advancing maternal age is due to failure of a postulated maternal screening process between fertilisation and recognition. This mechanism may also operate in other trisomies.

AB - Analysis of published data indicates that the increased rate of trisomy 21 pregnancies with advancing maternal age is due to failure of a postulated maternal screening process between fertilisation and recognition. This mechanism may also operate in other trisomies.

UR - https://www.scopus.com/pages/publications/0022577615

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ATTRITION OF TRISOMIES AS A MATERNAL SCREENING DEVICE. An Explanation of the Association of Trisomy 21 with Maternal Age

Abstract

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